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Article
Intermittent fasting promotes rejuvenation of immunosenescent phenotypes in aged adipose tissue
The aging of white adipose tissue (WAT) involves senescence of adipose stem and progenitor cells (ASPCs) and dysregulation of immune cell populations, serving as a major driver of age-associated adipose dysfun...
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Article
Open AccessImmune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive long term in allogeneic hosts
The immunogenicity of transplanted allogeneic cells and tissues is a major hurdle to the advancement of cell therapies. Here we show that the overexpression of eight immunomodulatory transgenes (Pdl1, Cd200, Cd47
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Article
Efficacy and safety of a home-use handheld multi-energy-based device for skin rejuvenation: clinical, ex vivo, and histological studies
Alongside increases in the average lifespan and a growing interest in anti-aging remedies, the demand for at-home skincare devices is rapidly expanding in the cosmetic market. This study aimed to assess the sa...
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Article
Open AccessPredicting the severity of postoperative scars using artificial intelligence based on images and clinical data
Evaluation of scar severity is crucial for determining proper treatment modalities; however, there is no gold standard for assessing scars. This study aimed to develop and evaluate an artificial intelligence m...
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Article
Anticancer activity of herbal formula Jisilhaebaekgyeji-Tang against human breast cancer cells and its mechanism
Jisilhaebaekgyeji-Tang (JHG, Zhishi **ebai Guizhi Tang) is a famous traditional herbal medicine described in the Geumgweyoryak (** Gui Yao Lue), an ancient Chinese medical text. JHG is composed of five medicinal...
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Article
Open AccessRecellularized lymph node scaffolds with human adipose-derived stem cells enhance lymph node regeneration to improve lymphedema
To overcome the limitations of lymphedema treatment, human adipose-derived stem cells (hADSCs) were injected into decellularized lymph nodes to produce a recellularized lymph node-scaffold, and the effect of l...
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Article
Non-epitaxial single-crystal 2D material growth by geometric confinement
Two-dimensional (2D) materials and their heterostructures show a promising path for next-generation electronics1–3. Nevertheless, 2D-based electronics have not been commercialized, owing mainly to three critical ...
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Article
Open AccessA biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the environment. This paper proposes a biomimetic ocular prosthesis system that m...
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Article
Contact hypersensitivity and Demodex mite infestation in patients with rosacea: a retrospective cohort analysis
Contact hypersensitivity or Demodex mite infestation is commonly reported in patients with rosacea. However, the associations and clinical implications of these two phenomena are poorly described in the literatur...
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Article
Safety of laparoscopic surgery during pregnancy: a Korean nationwide population-based study
The optimal surgical approach to perform during pregnancy is still controversial. This study evaluated pregnancy and operative outcomes in women undergoing an appendectomy or cholecystectomy during pregnancy, ...
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Article
Whole-genome sequencing revealed different demographic histories among the Korean endemic hill pigeon (Columba rupestris), rock pigeon (Columba livia var. domestica) and oriental turtle dove (Streptopelia orientalis)
The family Columbidae is known as the pigeon family and contains approximately 351 species and 50 genera. Compared to the wealth of biological and genomic information on these Columba livia var. domesteca, inform...
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Article
Open AccessPatient recalls associated with resident-to-attending radiology report discrepancies: predictive factors for risky discrepancies
This study aimed to identify predictive factors for risky discrepancies in the emergency department (ED) by analyzing patient recalls associated with resident-to-attending radiology report discrepancies (RRDs).
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Article
Open AccessPhysician adherence and patient-reported outcomes in heart failure with reduced ejection fraction in the era of angiotensin receptor-neprilysin inhibitor therapy
This Korean nationwide, multicenter, noninterventional, prospective cohort study aimed to analyze physician adherence to guideline-recommended therapy for heart failure (HF) with reduced ejection fraction (HFr...
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Article
Jageum-Jung, the herbal pharmaceuticals, inhibits the hepatic fibrogenesis as mediated with TGF-β1/smad signaling
Herbal prescriptions have various effects and their efficacy is potentiated by the use of combinations of medicinal herbs.
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Article
Open AccessImpact of diagnostic errors on adverse outcomes: learning from emergency department revisits with repeat CT or MRI
To investigate diagnostic errors and their association with adverse outcomes (AOs) during patient revisits with repeat imaging (RVRIs) in the emergency department (ED).
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Article
Increasing duration and intensity of nighttime supplemental lighting promotes growth and photosynthesis in young Cymbidium plants
This study was conducted to determine how nighttime supplemental lighting (NSL) duration and light intensity influence the growth and photosynthesis of young Cymbidium plants. Seven-month-old Cymbidium ‘Yang Guif...
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Article
Open AccessDischarge transition experienced by older Korean women after hip fracture surgery: a qualitative study
This study aimed to explore older Korean women’s discharge transition experiences after hip fracture surgery.
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Article
Open AccessControllable potential barrier for multiple negative-differential-transconductance and its application to multi-valued logic computing
Various studies on multi-valued-logic (MVL) computing, which utilizes more than two logic states, have recently been resumed owing to the demand for greater power saving in the current logic technologies. In p...
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Article
Open AccessAdministration of a herbal formulation enhanced blastocyst implantation via IκB activation in mouse endometrium
BaelanChagsangBang (BCB), a herbal formulation consisting of eleven herbs, may be prescribed as a reproductive functional supplement to improve ovulation and implantation during the treatment of infertility an...
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Article
Open AccessBlood pressure levels and cardiovascular risk according to age in patients with diabetes mellitus: a nationwide population-based cohort study
Little is known about age-specific target blood pressure (BP) in hypertensive patients with diabetes mellitus (DM). The aim of this study was to determine the BP level at the lowest cardiovascular risk of hype...
