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Article
Rezidivprävention der Urolithiasis
Die Urolithiasis ist eine der häufigsten urologischen Erkrankungen. Die Abklärung der Ursachen der Steinbildung bildet die Grundlage für eine erfolgreiche Rezidivprävention. Die metabolische Diagnostik und die...
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Article
Open AccessElucidating the need for prostate cancer risk calculators in conjunction with mpMRI in initial risk assessment before prostate biopsy at a tertiary prostate cancer center
Utilizing personalized risk assessment for clinically significant prostate cancer (csPCa) incorporating multiparametric magnetic resonance imaging (mpMRI) reduces biopsies and overdiagnosis. We validated both ...
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Article
Open AccessPsoas abscess in pregnancy: a review of the literature and suggestion of minimally invasive treatment options
Less than a dozen cases of psoas abscesses in pregnancy have been described in the literature. We reviewed the literature when treating a patient with a psoas abscess after ipsilateral double J-ureteral stent ...
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Article
Open AccessExpression of the microtubule-associated protein 2 (MAP2) as a potential independent prognostic marker in prostate cancer
Investigation of Microtubuli-associated Protein 2 (MAP2) expression and its clinical relevance in prostate cancer.
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Article
Open AccessDual-color DNA-PAINT single-particle tracking enables extended studies of membrane protein interactions
DNA-PAINT based single-particle tracking (DNA-PAINT-SPT) has recently significantly enhanced observation times in in vitro SPT experiments by overcoming the constraints of fluorophore photobleaching. However, ...
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Article
Open AccessCurrent role of systematic biopsy in diagnosis of clinically significant prostate cancer in primary combined MRI-targeted biopsy: a high-volume single-center study
Additive systematic biopsy (SB) contributes to prostate cancer (PCA) detection in MRI-targeted biopsy (TB). However, the reasons for this are not yet clear. We compared the performance of TB, SB and the combin...
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Article
Open AccessTracking single particles for hours via continuous DNA-mediated fluorophore exchange
Monitoring biomolecules in single-particle tracking experiments is typically achieved by employing fixed organic dyes or fluorescent fusion proteins linked to a target of interest. However, photobleaching typi...
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Article
An order of magnitude faster DNA-PAINT imaging by optimized sequence design and buffer conditions
DNA points accumulation in nanoscale topography (DNA-PAINT) is a relatively easy-to-implement super-resolution technique. However, image acquisition is slow compared to most other approaches. Here, we overcome...
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Article
Open AccessFlat-top TIRF illumination boosts DNA-PAINT imaging and quantification
Super-resolution (SR) techniques have extended the optical resolution down to a few nanometers. However, quantitative treatment of SR data remains challenging due to its complex dependence on a manifold of exp...
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Article
Open AccessFungaemia caused by obstructive renal candida bezoars leads to bilateral chorioretinitis: a case report
Renal fungal bezoars are remarkably rare and mostly occur in immunodeficient patients. Only a small number of cases with immunocompetent patients have been published so far. The published treatment approaches ...
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Article
Beigebrauchdetektion in der Substitutionstherapie
Die Gesundheit von Substitutionstherapiepatienten wird durch die Einnahme weiterer Drogen gefährdet. Daher verlangt die Bundesärztekammer den Nachweis therapiegetreuer Substituteinnahme. Testart und Überprüfun...
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Article
Open AccessMembranous CD24 expression as detected by the monoclonal antibody SWA11 is a prognostic marker in non-small cell lung cancer patients
Lung cancer is one of the most common malignant neoplasms worldwide and has a high mortality rate. To enable individualized therapy regimens, a better understanding of the molecular tumor biology has still to ...
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Article
Experimenteller Beitrag zur Frage des Reizobjektes der chronaximetrischen Prüfung der Hautsensibilität
