-
Article
Open AccessExpression of the microtubule-associated protein 2 (MAP2) as a potential independent prognostic marker in prostate cancer
Investigation of Microtubuli-associated Protein 2 (MAP2) expression and its clinical relevance in prostate cancer.
-
Article
Open AccessMembranous CD24 expression as detected by the monoclonal antibody SWA11 is a prognostic marker in non-small cell lung cancer patients
Lung cancer is one of the most common malignant neoplasms worldwide and has a high mortality rate. To enable individualized therapy regimens, a better understanding of the molecular tumor biology has still to ...
-
Article
Open AccessTuberous-sclerosis complex-related cell signaling in the pathogenesis of lung cancer
Hamartin (TSC1) and tuberin (TSC2), encoded by the tuberous sclerosis complex (TSC) genes, form a tumor-suppressor heterodimer which is implicated in PI3K-Akt signaling and acts as a functional inhibitor of the m...
-
Article
Open AccessMucosal atrophy in collagenous colitis: a case report
Mucosal atrophy as a potential cause of impaired colonic compliance has not yet been described as a complication in Collagenous Colitis (CC).
-
Article
Activation of Akt independent of PTEN and CTMP tumor-suppressor gene mutations in epilepsy-associated Taylor-type focal cortical dysplasias
Focal cortical dysplasias (FCD) with Taylor-type balloon cells (FCDIIb) are frequently observed in biopsy specimens of patients with pharmacoresistant focal epilepsies. The molecular pathogenesis of FCDIIb, which...
-
Article
Mutational and immunohistochemical analysis of ezrin-, radixin-, moesin (ERM) molecules in epilepsy-associated glioneuronal lesions
Glioneuronal lesions are frequently observed in biopsy specimens obtained from patients with pharmacoresistant epilepsies, comprising focal cortical dysplasias (FCD) and gangliogliomas. Recent findings point t...
