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  1. No Access

    Reference Work Entry In depth

    CDK11

    Dongli Hu, Jill M. Lahti in Encyclopedia of Signaling Molecules (2018)

  2. No Access

    Living Reference Work Entry In depth

    CDK11

    Dongli Hu, Jill M. Lahti in Encyclopedia of Signaling Molecules

  3. No Access

    Article

    Cyclin-dependent kinases: a family portrait

    Marcos Malumbres, Edward Harlow, Tim Hunt, Tony Hunter in Nature Cell Biology (2009)

  4. Article

    Open Access

    Two Isoforms of the Human Cyclin C Gene are Expressed Differentially Suggesting that they May Have Distinct Functions

    Cyclin C is a highly conserved protein that is involved in divergent cellular processes. The exact roles of its isoforms are presently not very well defined and it is possible that there is a functional diverg...

    R. L. Katona, P. Loyer, Sarah K. Roby, Jill M. Lahti in Acta Biologica Hungarica (2007)

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    Article

    Potentiation of neuroblastoma metastasis by loss of caspase-8

    Genetic alterations are common in aggressive neuroblastomas, the most common form of solid tumour in children. In particular the deletion or suppression of the apoptotic protease caspase 8 is common in maligna...

    Dwayne G. Stupack, Tal Teitz, Matthew D. Potter, David Mikolon, Peter J. Houghton in Nature (2006)

  6. Article

    Reply to “Expression and methylation of CASP8 in neuroblastoma: Identification of a promoter region”

    Tal Teitz, Jill M. Lahti, Vincent J. Kidd in Nature Medicine (2002)

  7. No Access

    Article

    Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN

    Important roles have been suggested for caspase-8, caspase-9 and Apaf-1 in controlling tumor development and their sensitivity to chemotherapeutic agents. Methylation and deletion of Apaf-1 and CASP8 results in t...

    Tal Teitz, Tie Wei, Dong Liu, Virginia Valentine, Marcus Valentine, Jose Grenet in Oncogene (2002)

  8. No Access

    Article

    Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death

    Neuroblastomas that overexpress N-Myc due to amplification of the MYCN oncogene are aggressive tumors that become very resistant to treatment by chemotherapy and irradiation. to identify tumor suppressor genes in...

    Tal Teitz, Jill M. Lahti, Vincent J. Kidd in Journal of Molecular Medicine (2001)

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    Article

    Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

    Caspase 8 is a cysteine protease regulated in both a death-receptor-dependent and -independent manner during apoptosis. Here, we report that the gene for caspase 8 is frequently inactivated in neuroblastoma, a...

    Tal Teitz, Tie Wei, Marcus B. Valentine, Elio F. Vanin, Jose Grenet in Nature Medicine (2000)

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    Article

    SHORT COMMUNICATIONS. Map** of five members of the cyclin gene family on chicken chromosomes by FISH

    Julio Masabanda, Robert Friedl, Alexei Sazanov, Jill M. Lahti in Chromosome Research (1998)

  11. Article

    Fas activates NF-κB and induces apoptosis in T-cell lines by signaling pathways distinct from those induced by TNF-α

    The p55 tumor necrosis factor (TNF) receptor and the Fas (CD95/APO-1) receptor share an intracellular domain necessary to induce apoptosis, suggesting they utilize common signaling pathways. To define pathways...

    Graham Packham, Jill M Lahti, Brian E Fee, Jonathan M Gawn in Cell Death & Differentiation (1997)

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    Chapter

    The PITSLRE protein kinase family

    A family of p34cdc2 related protein kinases, the PITSLRE kinases, is generated by alternative splicing and promoter utilization from three duplicated and tandemly linked genes on human chromosome 1p36.3, which is...

    Jill M. Lahti, Jialing **ang, Vincent J. Kidd in Progress in Cell Cycle Research (1995)

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    Chapter

    Cell Cycle-Related Protein Kinases and T Cell Death

    Programmed cell death (PCD), or apoptosis, involves the activation of a specific suicide program within a cell. PCD is responsible for such diverse activities as the elimination of cells during normal embryolo...

    Jill M. Lahti, Jialing **ang, Vincent J. Kidd in Glycoimmunology (1995)

  14. No Access

    Article

    Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma

    p58cdc2L1, a protein kinase implicated in apoptotic signaling, is one of eight separate kinases encoded by three tandemly duplicated and linked genes, which we have termed PITSLRE A, B and C. One allele of this c...

    Jill M. Lahti, Marcus Valentine, Jialing **ang, Bart Jones, Joseph Amann in Nature Genetics (1994)

  15. No Access

    Article

    Characterization of the avian T cell receptor

    Jill M. Lahti, Chen-Lo H. Chen, Joseph T. Sowder, R. Pat Bucy in Immunologic Research (1988)