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Open AccessAn estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2
Luminal breast cancer (BC) is a prevalent subtype associated with an increased risk of late disease recurrence and mortality. Long noncoding RNAs (lncRNAs) likely play significant roles in regulating tissue-sp...
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Article
Open AccessComparative single-cell analysis reveals heterogeneous immune landscapes in adenocarcinoma of the esophagogastric junction and gastric adenocarcinoma
Adenocarcinoma of the esophagogastric junction (AEG) is a type of tumor that arises at the anatomical junction of the esophagus and stomach. Although AEG is commonly classified as a subtype of gastric adenocar...
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Article
Human umbilical cord mesenchymal stem cell-derived exosomes carrying miR-1827 downregulate SUCNR1 to inhibit macrophage M2 polarization and prevent colorectal liver metastasis
microRNA-1827 (miR-1827) is proposed to be enriched in exosomes from mesenchymal stem cells (MSCs-Exos). A recent study has addressed the suppressive effect of exosomes from human umbilical cord mesenchymal st...
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Article
Open AccessIdentification of prognostic stemness biomarkers in colon adenocarcinoma drug resistance
Colon adenocarcinoma (COAD) is one of the leading causes of death worldwide. Cancer stem cells (CSCs) are vital for COAD chemoresistance and recurrence, however little is known about stem cell-related biomarke...
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Article
Open AccessFerroptosis-related gene SLC1A5 is a novel prognostic biomarker and correlates with immune infiltrates in stomach adenocarcinoma
Stomach adenocarcinoma (STAD) is associated with high morbidity and mortality rates. Ferroptosis is an iron-dependent form of cell death, which plays an important role in the development of many cancers. Tumor...
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Article
Open AccessCombining serum inflammation indexes at baseline and post treatment could predict pathological efficacy to anti‑PD‑1 combined with neoadjuvant chemotherapy in esophageal squamous cell carcinoma
The neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) have been used to predict therapeutic response in ...
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Article
Open AccessmicroRNA-96 promotes occurrence and progression of colorectal cancer via regulation of the AMPKα2-FTO-m6A/MYC axis
Colorectal cancer (CRC) is one of the frequently occurred malignancies in the world. To date, several onco-microRNAs (miRNAs or miRs), including miR-96, have been identified in the pathogenesis of CRC. In the ...
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Article
Open AccessAn Effect of Chronic Stress on Prospective Memory via Alteration of Resting-State Hippocampal Subregion Functional Connectivity
The alteration of hippocampal function by chronic stress impairs higher order cognitive functions such as prospective memory (PM). However, how chronic stress affects hippocampal subregions related to PM remai...
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Article
Degradation of Selected Organophosphate Pesticides in Wastewater by Dielectric Barrier Discharge Plasma
In this paper, degradation of selected organophosphate pesticides (dichlorvos and dimethoate) in wastewater by dielectric barrier discharge plasma (DBD) was studied. DBD parameters, i.e. discharge powers and a...
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Article
Surface free energies and steam stability of methyl-modified silica membranes
Methyl-modified silica membranes have been prepared by acid-catalyzed co-hydrolysis and condensation reactions of tetraethylorthosilicate (TEOS) and methyltriethoxysilane (MTES). The surface wettability, micro...
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Article
Remote Oxygen and Nitrogen Plasma Inactivation of Staphylococcus aureus: Effects and Mechanisms
The distribution of active species in remote oxygen and nitrogen plasma and the germicidal effect (GE) of Staphylococcus aureus on the surface of medical poly(tetrafluoroethylene), polyvin...
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Article
Surface modification of poly (vinyl chloride) by long-distance and direct argon RF plasma
This paper reports the effects of long-distance and direct argon radio frequency (RF) plasma surface treatment on polyvinyl chloride (PVC) films in terms of changes in surface wettability and surface chemistry...