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Chapter
Risk of High-Grade Malignancy (ROHM)
Based on the premise of The Paris System for Reporting Urinary Cytology (TPS), that the main goal of urine cytology is the detection of clinically significant cancers, particularly high-grade urothelial carcin...
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Chapter
Liquid Biopsy
Over the years, precision medicine has revolutionized the management strategies for cancer, with the aim of achieving early diagnosis and individualized treatment. This requires effective integration of a larg...
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Article
Open AccessPiezoelectric needle sensor reveals mechanical heterogeneity in human thyroid tissue lesions
Palpable thyroid lesions are common, and although mostly benign, lethal malignant nodules do occur and may be difficult to differentiate. Here, we introduce the use of a piezoelectric system called Smart-touch...
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Article
Open AccessEffects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol
To study the effects of supplementation of a marine omega-3 poly-unsaturated fatty acids (n3-PUFA) formulation (Omega3Q10) in older adults with hypertension and/or hypercholesterolemia.
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Article
Open AccessEffects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo-controlled trial
Recent experiments suggest that Citrus bergamia extracts could benefit people with dyslipidemia and obesity but this needs to be further validated.
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Article
Open AccessLabel-free enumeration, collection and downstream cytological and cytogenetic analysis of circulating tumor cells
Circulating tumor cells (CTCs) have a great potential as indicators of metastatic disease that may help physicians improve cancer prognostication, treatment and patient outcomes. Heterogeneous marker expressio...
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Article
Open AccessEffects of G.H.3. On mental symptoms and health-related quality of life among older adults: results of a three-month follow-Up study in Shanghai, China
To explore the effects of daily use of Gerovital H3 (G.H.3.) tablets on relieving mental symptoms and improving health-related quality of life among Chinese older adults population.
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Book
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Article
Open AccessScreening cell mechanotype by parallel microfiltration
Cell mechanical phenotype or ‘mechanotype’ is emerging as a valuable label-free biomarker. For example, marked changes in the viscoelastic characteristics of cells occur during malignant transformation and can...
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Article
Multicenter evaluation of the role of UroVysion FISH assay in surveillance of patients with bladder cancer: does FISH positivity anticipate recurrence?
The significance of a positive UroVysion FISH assay is uncertain in patients with normal cystoscopy. This multicenter study evaluates the clinical significance of a positive FISH assay in patients with no visi...
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Article
Open AccessMacrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma
Macrophage inhibitory cytokine 1 (MIC-1/GDF15) has been identified as a potential novel biomarker for detection of pancreatic cancer (PCa). However, the diagnostic value of serum MIC-1 for pancreatic ductal ad...
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Article
Open AccessLongitudinal trends in prostate cancer incidence, mortality, and survival of patients from two Shanghai city districts: a retrospective population-based cohort study, 2000–2009
Prostate cancer is the fifth most common cancer affecting men of all ages in China, but robust surveillance data on its occurrence and outcome is lacking. The specific objective of this retrospective study was...
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Article
Genetic variation at 8q24, family history of cancer, and upper gastrointestinal cancers in a Chinese population
Genetic variation at 8q24 is associated with prostate, bladder, breast, colorectal, thyroid, lung, ovarian, UADT, liver and stomach cancers. However, a role for variation at 8q24 in familial clustering of uppe...
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Article
Open AccessEffects of Lung Support Formula on respiratory symptoms among older adults: results of a three-month follow-up study in Shanghai, China
With the acceleration of industrialization in low or middle-income nations, the prevalence of respiratory symptoms among older adults is even more significant now in China. Contemporary treatments using Wester...
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Article
Open AccessEstradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-posit...
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Article
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4
Yinghao Sun and colleagues report a genome-wide association study for prostate cancer in Han Chinese men. They identify two new risk-associated loci at chromosomes 9q31 and 19q13.
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Chapter
Evidence-based Anticancer Materia Medica for Bladder Cancer
Bladder cancer is a relatively common urinary tract carcinoma. There are in general two categories of bladder cancer, low grade and high grade, which develop through distinct molecular pathways, have different...
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Article
Open AccessA novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases
The lack of sufficient specificity and sensitivity among conventional cancer biomarkers, such as prostate specific antigen (PSA) for prostate cancer has been widely recognized after several decades of clinical...
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Article
Applicability of AFM in cancer detection
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Article
Open AccessEffects of AR7 Joint Complex on arthralgia for patients with osteoarthritis: Results of a three-month study in Shanghai, China
Osteoarthritis-induced arthralgia is a common cause of morbidity in both men and women worldwide. AR7 Joint Complex is a nutritional supplement containing various ingredients including sternum collagen II and ...
