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  1. Article

    Open Access

    Pharmacokinetics of phenoxodiol, a novel isoflavone, following intravenous administration to patients with advanced cancer

    Phenoxodiol is a novel isoflavone currently being studied in clinical trials for the treatment of cancer. This study reports the pharmacokinetics of phenoxodiol in patients with cancer.

    Jan B Howes, Paul L de Souza, Leanne West, Li Jiu Huang in BMC Clinical Pharmacology (2011)

  2. No Access

    Article

    Phase Ib Single- and Multiple-Dose Pharmacokinetic Study of Oral NV-52 in Healthy Volunteers

    Background and objective: NV-52 is a novel synthetic flavonoid thromboxane synthase (TXS) inhibitor that may be useful for the maintenance of remission in inflammatory bowel disease (IBD). This s...

    Dr Laurence G. Howes, Jan B. Howes, Jiu Li Huang, Catherine Walker in Drugs in R & D (2008)