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  1. No Access

    Article

    Phase Ib Single- and Multiple-Dose Pharmacokinetic Study of Oral NV-52 in Healthy Volunteers

    Background and objective: NV-52 is a novel synthetic flavonoid thromboxane synthase (TXS) inhibitor that may be useful for the maintenance of remission in inflammatory bowel disease (IBD). This s...

    Dr Laurence G. Howes, Jan B. Howes, Jiu Li Huang, Catherine Walker in Drugs in R & D (2008)

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    Article

    Selective Cyclo-Oxygenase-2 Inhibitors and Myocardial Infarction

    There are concerns that selective cyclo-oxygenase (COX)-2 inhibitors may be prothrombotic and increase the risk of myocardial infarction. This has largely arisen because of an unexpected finding of a higher ra...

    Dr Laurence G. Howes, Henry Krum in Drug Safety (2002)