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  1. No Access

    Article

    Subetta Enhances Sensitivity of Human Muscle Cells to Insulin

    Addition of Subetta to insulin (10 nM) increased insulin-stimulated glucose uptake 43% (p<0.001). Moreover, glucose uptake stimulated by insulin (10 nM) in the presence of Subetta was similar to that stimulated b...

    E. A. Gorbunov, J. Nicoll, A. A. Myslivets… in Bulletin of Experimental Biology and Medic… (2015)

  2. Article

    Open Access

    Subetta increases phosphorylation of insulin receptor β-subunit alone and in the presence of insulin

    It has been previously shown that Subetta (a drug containing released-active forms of antibodies to the insulin receptor β-subunit and antibodies to endothelial nitric oxide synthase) stimulated insulin-induce...

    E A Gorbunov, J Nicoll, E V Kachaeva, S A Tarasov, O I Epstein in Nutrition & Diabetes (2015)

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  3. No Access

    Article

    The potential for efficacy of the modified (ICP 34.5−) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study

    We have previously demonstrated the safety of intratumoural administration of the selectively replication-competent herpes simplex virus mutant HSV1716 in patients with high-grade glioma (HGG). Here we show it...

    V Papanastassiou, R Rampling, M Fraser, R Petty, D Hadley, J Nicoll… in Gene Therapy (2002)

  4. No Access

    Chapter and Conference Paper

    Microvascular Pathology in Familial Multiinfarct Dementia or CADASIL: Implications for Cerebral Blood Flow

    Recent reports suggest the existence of several forms of hereditary cerebrovascular disease leading to multiinfarct dementia or vascular dementia. The most common form of familial vascular dementia appears to ...

    R. N. Kalaria, N. J. Cookson, T. Mizuno, A. Oakley… in Ischemic Blood Flow in the Brain (2001)

  5. No Access

    Article

    Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

    The herpes simplex virus (HSV) ICP34.5 null mutant 1716 replicates selectively in actively dividing cells and has been proposed as a potential treatment for cancer, particularly brain tumours. We present a cli...

    R Rampling, G Cruickshank, V Papanastassiou, J Nicoll, D Hadley, D Brennan… in Gene Therapy (2000)

  6. No Access

    Article

    Inhomogeneous and homogeneous broadening effects onnuclear resonance experiments

    Inhomogeneous broadening of resonance lines causes a reduction of absorption in nuclear resonance experiments. This is particularly devastating to the observation of the Mössbauer effect in isomers like 107Ag wit...

    B. Balko, I.W. Kay, J. Nicoll, J.D. Silk, G. Herling in Hyperfine Interactions (1997)

  7. No Access

    Article

    Total and peripheral bone mass in patients with psoriatic arthritis and rheumatoid arthritis

    Psoriatic arthritis is thought to be associated with periarticular osteoporosis while rheumatoid arthritis may be associated with generalised as well as periarticular bone loss. To assess...

    Dr. D. M. Reid, N. S. J. Kennedy, J. Nicoll, M. A. Smith… in Clinical Rheumatology (1986)