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  1. Article

    Open Access

    Interleukin-6 gene amplification and shortened survival in glioblastoma patients

    Interleukin-6 (IL-6) is known to promote tumour growth and survival. We evaluated IL-6 gene amplification in tumours from 53 glioma patients using fluorescence in situ hybridisation. Amplification events were det...

    A Tchirkov, T Khalil, E Chautard, K Mokhtari, L Véronèse in British Journal of Cancer (2007)

  2. Article

    Open Access

    Clinical implications of quantitative real-time RT–PCR analysis of hTERT gene expression in human gliomas

    The presence of telomerase activity in a glioma may be a predictor of its malignant potential. Activation of telomerase is regulated at the transcriptional level of the human telomerase reverse transcriptase (hTE...

    A Tchirkov, C Rolhion, J-L Kémény, B Irthum, S Puget, T Khalil in British Journal of Cancer (2003)