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  1. Article

    Open Access

    Clinical implications of quantitative real-time RT–PCR analysis of hTERT gene expression in human gliomas

    The presence of telomerase activity in a glioma may be a predictor of its malignant potential. Activation of telomerase is regulated at the transcriptional level of the human telomerase reverse transcriptase (hTE...

    A Tchirkov, C Rolhion, J-L Kémény, B Irthum, S Puget, T Khalil in British Journal of Cancer (2003)

  2. Article

    Open Access

    IL-6 gene amplification and expression in human glioblastomas

    The aggressiveness of human gliomas appears to be correlated with the upregulation of interleukin 6 (IL-6) gene. Using quantitative PCR methods, we detected amplification and expression of the IL-6 gene in 5 of 5...

    A Tchirkov, C Rolhion, S Bertrand, J-F Doré, J-J Dubost in British Journal of Cancer (2001)