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  1. Article

    Response to Dr McNab

    J G Heathcote, A A Valenzuela in Eye (2012)

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  2. Article

    Isolated eyelid edema in Melkersson–Rosenthal syndrome: a case series

    To report the clinicopathologic features of a series of patients with Melkersson–Rosenthal syndrome (MRS).

    N G Rawlings, A A Valenzuela, L H Allen, J G Heathcote in Eye (2012)

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    Article

    Osteogenesis imperfecta: Evidence for the existence of an abnormal amino acid sequence in the molecule of dermal collagen

    A collagen-type pattern of peptide and amino acid spots was obtained when partial hydrolysates of normal human dermis were examined by a specially developed thin-layer chromatographic (TLC) ‘finger-printing’ t...

    J. G. Heathcote, Samirah Al-Alawi in Journal of Inherited Metabolic Disease (1978)

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    Article

    Percutaneous electrophoresis of amino acids and urea

    A noninvasive method for the percutaneous extraction and determination of samples of metabolites is described. It involves the use of a battery-operated, constant-current supply for obtaining the samples by ‘i...

    S. Y. Shaya, C. W. Smith, J. G. Heathcote in Medical and Biological Engineering and Com… (1978)

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    Article

    Biological Activity and Electronic Structure of the Aflatoxins

    In theoretical studies of aromatic hydrocarbons, Pullman and Pullman (1969) used the molecular orbital method to correlate electronic structure with biological activity. They suggested that the interaction bet...

    J G Heathcote, J R Hibbert in British Journal of Cancer (1974)

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    Article

    The analysis by TLC of the amino acids of protein hydrolysates and of biological fluids

    The degree of sensitivity and of resolution of amino acids which is possible with TLC is much higher than with paper chromatography. This makes TLC on cellulose powder an ideal system for the analysis of prote...

    J. G. Heathcote in Qualitas Plantarum et Materiae Vegetabiles (1968)

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    Article

    Oral Treatment of Pernicious Anaemia

    IT will not surprise many workers in the B12 field to read that Dr. Heinivaara and Dr. Palva have obtained a remission over a period of 50 days in one case of pernicious anaemia, which was receiving a daily dosag...

    F. S. MOONEY, J. G. HEATHCOTE in Nature (1965)

  8. Article

    Absorption of Vitamin B12-Glutamic Acid Mixture

    THE authors of the preceding communication state that “According to them [Heathcote and Mooney], vitamin B12 is absorbed as either small peptide or amino-acid units”. We trust that this misinterpretation of our a...

    F. S. MOONEY, J. G. HEATHCOTE in Nature (1963)

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    Article

    Oral Treatment of Pernicious Anæmia with a Vitamin B12/L~Glutamic Acid Mixture

    ACCORDING to Castle1, pernicious anæmia is due to failure of the stomach to secrete a high-molecular-weight, non-dialysable protein (intrinsic factor) which facilitates the absorption of pure vitamin B12 (extrins...

    J. G. HEATHCOTE, F. S. MOONEY in Nature (1962)

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    Article

    Inhibition of the Growth of Leuconostoc mesenteroides by the Toxic Factor from ‘Agenized’ Zein: Reversal by L-Glutamine

    THE crystalline toxic factor originally isolated1 from zein treated with nitrogen trichloride causes epileptiform fits in certain animals and inhibits the growth of Leuconostoc mesenteroides P-602. The subsequent...

    J. G. HEATHCOTE, J. PACE in Nature (1950)

  11. Article

    Toxic Effect of the Crystals from ‘Agenized’ Zein on Certain Acid-producing Bacteria

    THE crystalline material described above has been tested against several organisms used chiefly for microbiological assay. These tests have shown that the crystals are markedly toxic to the organism Leuconostoc m...

    J. G. HEATHCOTE in Nature (1949)

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    Article

    Action of Nitrogen Trichloride on Proteins : Production of Toxic Derivative

    FOLLOWING Mellanby‘s discovery1 that ‘‘Agenized wheaten flour, when fed to dogs, produces hysteria, it was shown in a first paper2 from these laboratories that the syndrome is not due to a nutritional deficiency ...

    H. R. BENTLEY, R. G. BOOTH, E. N. GREER, J. G. HEATHCOTE, J. B. HUTCHINSON… in Nature (1948)