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  1. Article

    Open Access

    Alpha peak frequency-based Brainmarker-I as a method to stratify to pharmacotherapy and brain stimulation treatments in depression

    Biomarkers predicting treatment outcome in major depressive disorder could enhance clinical improvement. Here this observational and prospective accuracy study investigates whether an age- and sex-normalized e...

    Helena T. S. Voetterl, Alexander T. Sack, Sebastian Olbrich in Nature Mental Health (2023)

  2. Article

    Open Access

    rTMS combined with CBT as a next step in antidepressant non-responders: a study protocol for a randomized comparison with current antidepressant treatment approaches

    Major depressive disorder (MDD) is one of the most common psychiatric disorders, however, current treatment options are insufficiently effective for about 35% of patients, resulting in treatment-resistant depr...

    Iris Dalhuisen, Filip Smit, Jan Spijker, Iris van Oostrom, Eric van Exel in BMC Psychiatry (2022)

  3. Article

    Open Access

    Is a Negative Attentional Bias in Individuals with Autism Spectrum Disorder Explained by Comorbid Depression? An Eye-Tracking Study

    Heightened attention towards negative information is characteristic of depression. Evidence is emerging for a negative attentional bias in Autism spectrum disorder (ASD), perhaps driven by the high comorbidity...

    M. Annemiek Bergman, Janna N. Vrijsen in Journal of Autism and Developmental Disord… (2021)

  4. Article

    Open Access

    ADHD symptoms in healthy adults are associated with stressful life events and negative memory bias

    Stressful life events, especially Childhood Trauma, predict ADHD symptoms. Childhood Trauma and negatively biased memory are risk factors for affective disorders. The association of life events and bias with A...

    Janna N. Vrijsen, Indira Tendolkar in ADHD Attention Deficit and Hyperactivity D… (2018)

  5. Article

    Childhood abuse and deprivation are associated with distinct sex-dependent differences in brain morphology

    Childhood adversity (CA) has been associated with long-term structural brain alterations and an increased risk for psychiatric disorders. Evidence is emerging that subtypes of CA, varying in the dimensions of ...

    Daphne Everaerd, Floris Klumpers, Marcel Zwiers, Tulio Guadalupe in Neuropsychopharmacology (2016)

  6. No Access

    Article

    Coherence Between Attentional and Memory Biases in Sad and Formerly Depressed Individuals

    Cognitive theories assume a uniform processing bias across different samples, but the empirical support for this claim is rather weak and inconsistent. Therefore, coherence between biases across different cogn...

    Janna N. Vrijsen, Iris van Oostrom, Linda Isaac in Cognitive Therapy and Research (2014)

  7. No Access

    Article

    Can Memory Bias be Modified? The Effects of an Explicit Cued-Recall Training in Two Independent Samples

    Cognitive bias modification (CBM) has been found to be effective in modifying information-processing biases and in reducing emotional reactivity to stress. Although modification of attention and interpretation...

    Janna N. Vrijsen, Eni S. Becker, Mike Rinck in Cognitive Therapy and Research (2014)

  8. Article

    Open Access

    Approach and Avoidance of Emotional Faces in Happy and Sad Mood

    Since the introduction of the associative network theory, mood-congruent biases in emotional information processing have been established in individuals in a sad and happy mood. Research has concentrated on me...

    Janna N. Vrijsen, Iris van Oostrom, Anne Speckens in Cognitive Therapy and Research (2013)

  9. Article

    Sex Modulates the Interactive Effect of the Serotonin Transporter Gene Polymorphism and Childhood Adversity on Hippocampal Volume

    The common genetic variation of the serotonin transporter-linked polymorphic region (5-HTTLPR) has been related to depressive symptoms, in particular after stressful life events. Although it has been investiga...

    Daphne Everaerd, Lotte Gerritsen, Mark Rijpkema, Thomas Frodl in Neuropsychopharmacology (2012)

  10. Article

    Open Access

    Presymptomatic DNA Testing in BRCA1/2. Invited reactions from the field on the van Oostrom and Tibben paper

    Rolf H. Sijmons, Rodney J. Scott, Jan Lubiñski in Hereditary Cancer in Clinical Practice (2004)

  11. Article

    Open Access

    A Counselling Model for BRCA1/2 Genetic Susceptibility Testing

    When BRCA1/2 genetic susceptibility testing was introduced in the clinic in the mid-nineties, the "Huntington protocol" was used in the counselling of individuals applying for genetic testing. This protocol inclu...

    Iris van Oostrom, Aad Tibben in Hereditary Cancer in Clinical Practice (2004)

  12. No Access

    Article

    Kijken in de glazen bolerfelijkheid voorspellende diagnostiek erfelijke borst- en ovariumkanker

    Voorspellen of je in de toekomst mogelijk een ernstige ziekte zoals kanker zult krijgen is geen science fiction meer. Sinds enkele jaren kunnen mensen uit families waar een afwijkend gen is gevonden laten onde...

    Iris van Oostrom, Aad Tibben in Psychopraxis (2003)