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Article
Open AccessThe structural variation landscape in 492 Atlantic salmon genomes
Structural variants (SVs) are a major source of genetic and phenotypic variation, but remain challenging to accurately type and are hence poorly characterized in most species. We present an approach for reliab...
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Chapter and Conference Paper
Automated Business Process Discovery from Unstructured Natural-Language Documents
Understanding the processes followed by organizations is important to ensure business outcomes are achieved in an optimal, efficient and compliant manner. Process mining techniques rely on the existence of str...
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Chapter
The European Marine Biological Research Infrastructure Cluster: An Alliance of European Research Infrastructures to Promote the Blue Bioeconomy
Marine biotechnology is the key to harness the huge economic potential of the unique biodiversity of marine organisms. This potential remains largely underexploited due to three major issues: (1) lack of conne...
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Article
Open AccessRNAseq analysis of fast skeletal muscle in restriction-fed transgenic coho salmon (Oncorhynchus kisutch): an experimental model uncoupling the growth hormone and nutritional signals regulating growth
Coho salmon (Oncorhynchus kisutch) transgenic for growth hormone (Gh) express Gh in multiple tissues which results in increased appetite and continuous high growth with satiation feeding. Restricting Gh-transgeni...
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Article
Open AccessCharacterisation and expression analysis of cathepsins and ubiquitin-proteasome genes in gilthead sea bream (Sparus aurata) skeletal muscle
The proteolytic enzymes involved in normal protein turnover in fish muscle are also responsible for post-mortem softening of the flesh and are therefore potential determinants of product quality. The main enzyme ...
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Article
Open AccessCharacterization of the transcriptome of fast and slow muscle myotomal fibres in the pacu (Piaractus mesopotamicus)
The Pacu (Piaractus mesopotamicus) is a member of the Characiform family native to the Prata Basin (South America) and a target for the aquaculture industry. A limitation for the development of a selective breedi...
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Article
Open AccessProfiling of the embryonic Atlantic halibut (Hippoglossus hippoglossus L.) transcriptome reveals maternal transcripts as potential markers of embryo quality
Commercial Atlantic halibut (Hippoglossus hippoglossus) farming is restricted by variable oocyte quality, slow growth, and early maturation of male fish. Maternally transferred components regulate early developme...
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Article
Open AccessFast skeletal muscle transcriptome of the Gilthead sea bream (Sparus aurata) determined by next generation sequencing
The gilthead sea bream (Sparus aurata L.) occurs around the Mediterranean and along Eastern Atlantic coasts from Great Britain to Senegal. It is tolerant of a wide range of temperatures and salinities and is ofte...
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Article
Open AccessMaternal gene expression in Atlantic halibut (Hippoglossus hippoglossus L.) and its relation to egg quality
The commercial production of Atlantic halibut (Hippoglossus hippoglossus L.) suffers from a major bottleneck due to the low success of producing juveniles for on-growing. Atlantic halibut females are routinely ha...
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Article
Gene expression analyses of essential catch factors in the smooth and striated adductor muscles of larval, juvenile and adult great scallop (Pecten maximus)
The scallop adductor muscle consists of striated fibres responsible for the fast closure of the shells, and smooth fibres able to maintain tension in a prolonged state of contraction called catch. Formation of...
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Article
Open AccessPhasing of muscle gene expression with fasting-induced recovery growth in Atlantic salmon
Many fish species experience long periods of fasting in nature often associated with seasonal reductions in water temperature and prey availability or spawning migrations. During periods of nutrient restrictio...
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Article
Open AccessSelection of reference genes for expression studies with fish myogenic cell cultures
Relatively few studies have used cell culture systems to investigate gene expression and the regulation of myogenesis in fish. To produce robust data from quantitative real-time PCR mRNA levels need to be norm...
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Article
Open AccessEvolution of the multifaceted eukaryotic akiringene family
Akirins are nuclear proteins that form part of an innate immune response pathway conserved in Drosophila and mice. This studies aim was to characterise the evolution of akirin gene structure and protein function ...
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Article
Effect of natural selection on the duplicated lysyl oxidase gene in Atlantic salmon
We examined the polymorphism of the lysyl oxidase (LOX) locus, involved in the initiation of muscle collagen cross-linking, in three populations of Atlantic salmon with different life histories and growth rates a...
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Article
Evolution of follistatin in teleosts revealed through phylogenetic, genomic and expression analyses
Follistatin (Fst) inhibits transforming growth factor-β (TGF-B) proteins and is a known regulator of amniote myogenesis. Here, we used phylogenetic, genomic and experimental approaches to study its evolution i...
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Article
Invertebrate muscle performance at high latitude: swimming activity in the Antarctic scallop, Adamussium colbecki
The escape swimming performance of the Antarctic scallop, Adamussium colbecki, was measured in animals acclimated for 6 weeks to −1, 0 or 2°C and tested at −1.5 to +1.5°C. Clap duration and swimming velocity were...
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Article
Genomics: applications to Antarctic ecosystems
Biological research in Antarctica has made considerable progress in science over recent decades. As little as 50 years ago, there was scant knowledge even of the species inhabiting the region. Since then, unde...
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Article
Temperature and developmental plasticity during embryogenesis in the Atlantic cod Gadus morhua L.
Atlantic cod (Gadus morhua L.) embryos were reared at 4 °C, 7 °C, and 10 °C, and the relative timing of developmental events was characterized, with particular reference to myotomal muscle. Embryos started to fee...
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Chapter
Genes regulating the growth of myotomal muscle in teleost fish
Postembryonic muscle growth in fish differs from that in mammals in that new muscle fibres continue to be produced throughout much of the life cycle. Growth involves the proliferation of a population of myogen...
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Chapter
Phenotypic plasticity of fish muscle to temperature change
The swimming performance of teleost fish is highly dependent on temperature. Natural selection has acted to adjust locomotory performance to particular thermal environments involving selective changes at the l...
