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Article
Open AccessIn vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS) is a form of motor neuron disease (MND) that is characterized by the progressive loss of motor neurons within the spinal cord, brainstem, and motor cortex. Although ALS clin...
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Article
Open AccessIn vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
The skeletal muscle T-tubule is a specialized membrane domain essential for coordinated muscle contraction. However, in the absence of genetically tractable systems the mechanisms involved in T-tubule formatio...
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Protocol
Live Confocal Imaging of Zebrafish Notochord Cells Under Mechanical Stress In Vivo
The zebrafish is a vertebrate model suited to the exploration of cell biology within a whole organism. Hypotheses in cell mechanics can be tested by using the zebrafish notochord as a manipulable experimental ...
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Article
A somitic contribution to the apical ectodermal ridge is essential for fin formation
Invasion of a somite-derived cell population into the apical ectodermal ridge in zebrafish regulates apical fold induction during fin formation; ablation of these cells inhibits formation of the apical fold an...
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Article
Open AccessZebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function
Nemaline myopathy is characterized by muscle weakness and the presence of rod-like (nemaline) bodies. The genetic etiology of nemaline myopathy is becoming increasingly understood with mutations in ten genes n...
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Chapter and Conference Paper
Perfect Sequences of Unbounded Lengths over the Basic Quaternions
In this paper we show the existence of perfect sequences, of unbounded lengths, over the basic quaternions {1, − 1,i, − i,j, − j,k, − k}. Perfect sequences over the quaternion algebra were first introduced in 200...
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Article
Open AccessFishNet: an online database of zebrafish anatomy
Over the last two decades, zebrafish have been established as a genetically versatile model system for investigating many different aspects of vertebrate developmental biology. With the credentials of zebrafis...
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Article
Temperature and developmental plasticity during embryogenesis in the Atlantic cod Gadus morhua L.
Atlantic cod (Gadus morhua L.) embryos were reared at 4 °C, 7 °C, and 10 °C, and the relative timing of developmental events was characterized, with particular reference to myotomal muscle. Embryos started to fee...
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Chapter
Genes regulating the growth of myotomal muscle in teleost fish
Postembryonic muscle growth in fish differs from that in mammals in that new muscle fibres continue to be produced throughout much of the life cycle. Growth involves the proliferation of a population of myogen...
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Chapter
Ultra Wide Band Millimeter Wave Holographic “3-D” Imaging of Concealed Targets on Mannequins
Ultra wide band (chirp frequency) millimeter wave “3-D” holography is a unique technique for imaging concealed targets on human subjects with extremely high lateral and depth resolution. Recent “3-D” holograph...
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Article
McCallum’s base growth rule: Results for the United States, West Germany, Japan, and Canada
The results presented here suggest that McCallum’s rule for base growth deserves serious consideration by policymakers. The rule is extremely simple and the results here indicate that the growth rule may go a ...
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Chapter
Computer Holographic Reconstruction System Implementing Integrated Three Dimensional Multi-Image Technique
This paper describes a computer (Fresnel/Fourier transform) holographic reconstruction system used in the inspection of nuclear pressure vessels. The computer system can generate quasi-real-time (128x128) holo...
