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  1. Article

    Open Access

    Exosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis

    This study aims to investigate the potential anti-inflammatory effects of exosomes engineered to carry super-repressor IκB (Exo-srIκB), an exosome-based NF-κB inhibitor, in the context of RA.

    Hae-In Lee, Min-Joo Ahn, Jae-Kwang Yoo, So-Hee Ahn in Arthritis Research & Therapy (2024)

  2. No Access

    Article

    Fluorescent Lateral Flow Assay with Carbon Nanodot Conjugates for Carcinoembryonic Antigen

    A lateral flow assay (LFA) sensor on a half-strip platform labeled with blue carbon nanodot-polystyrene (PS-CND) nanoconjugates was developed for the detection of carcinoembryonic antigen (CEA) levels in buffe...

    Jung Min Lim, Mulya Supianto, Tae Yang Kim, Byeong Soo Kim in BioChip Journal (2023)

  3. Article

    Open Access

    Effects of Helichrysum bracteatum flower extracts on UVB irradiation-induced inflammatory biomarker expression

    The present study aimed to investigate the anti-inflammatory activity of Helichrysum bracteatum (H. bracteatum) flower extracts in vitro.

    Yun Jeong Kim, Ji Hyun Seok, Waiting Cheung, Sung-Nae Lee in Biomedical Dermatology (2019)

  4. Article

    Open Access

    Effects of the myrtle essential oil on the acne skin—clinical trials for Korean women

    This study aims to clinically verify the effects of myrtle essential oil, which has non-irritation, non-toxicity, and non-sensitivity characteristics among natural materials, by applying the oil to acne skin o...

    Kyung Yun Kim, Hyun Hee Jang, Sung Nae Lee, Young-Sam Kim in Biomedical Dermatology (2018)

  5. Article

    Open Access

    Protective effect of protocatechuic acid against inflammatory stress induced in human dermal fibroblasts

    Protocatechuic acid (PCA) is an anthocyanin metabolite with a high antioxidant property. It is also known for having anticancer and anti-inflammatory capacities with diverse medicinal activities. As one of the...

    Ji Hye Son, Soo-Yeon Kim, Hyun Hee Jang, Sung Nae Lee in Biomedical Dermatology (2018)

  6. No Access

    Article

    Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite

    To find a simple enzymatic strategy for the efficient synthesis of the expensive 5′-hydroxyomeprazole sulfide, a recently identified minor human metabolite, from omeprazole sulfide, which is an inexpensive sub...

    Hyun-Hee Jang, Sang-Hoon Ryu, Thien-Kim Le, Tiep Thi My Doan in Biotechnology Letters (2017)

  7. No Access

    Article

    Benzo(a)pyrene represses melanogenesis in B16F10 mouse melanoma cells

    Benzo(a)pyrene (BaP) is a chemically based polycyclic aromatic hydrocarbon (PAH) that is readily absorbed by the skin. BaP is metabolized to BaP-diol-epoxide by cytochromes P-450 1A1/2 (CYP1A1/2) and cytochrom...

    Da Hye Joo, Hwa Jun Cha, Karam Kim, Minhee Jung in Molecular & Cellular Toxicology (2015)

  8. No Access

    Article

    Impact of lysophosphatidylcholine on survival and function of UEA-1+acLDL+ endothelial progenitor cells in patients with coronary artery disease

    Lysophosphatidylcholine (LPC) generated from oxidized low-density lipoprotein by lipoprotein-associated phospholipase A2 plays a key role in plaque inflammation and vulnerability. Endothelial progenitor cells...

    Seong Hun Hong, Hyun Hee Jang, So Ra Lee, Kyung Hye Lee, Jong Shin Woo in Heart and Vessels (2015)