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    Article

    Peroxide-dependent oxidation reactions catalyzed by CYP191A1 from Mycobacterium smegmatis

    To find the catalytic activities of CYP191A1 from Mycobacterium smegmatis, in which functions of most P450s are unknown, by using a set of reductase systems, peroxides, and various substrates including fatty acid...

    Hye-Yeong Jo, Sun-Ha Park, Thien-Kim Le, Sang Hoon Ma, Donghak Kim in Biotechnology Letters (2017)

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    Article

    Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite

    To find a simple enzymatic strategy for the efficient synthesis of the expensive 5′-hydroxyomeprazole sulfide, a recently identified minor human metabolite, from omeprazole sulfide, which is an inexpensive sub...

    Hyun-Hee Jang, Sang-Hoon Ryu, Thien-Kim Le, Tiep Thi My Doan in Biotechnology Letters (2017)