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Article
Open AccessExosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis
This study aims to investigate the potential anti-inflammatory effects of exosomes engineered to carry super-repressor IκB (Exo-srIκB), an exosome-based NF-κB inhibitor, in the context of RA.
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Article
Fluorescent Lateral Flow Assay with Carbon Nanodot Conjugates for Carcinoembryonic Antigen
A lateral flow assay (LFA) sensor on a half-strip platform labeled with blue carbon nanodot-polystyrene (PS-CND) nanoconjugates was developed for the detection of carcinoembryonic antigen (CEA) levels in buffe...
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Article
Open AccessEffects of Helichrysum bracteatum flower extracts on UVB irradiation-induced inflammatory biomarker expression
The present study aimed to investigate the anti-inflammatory activity of Helichrysum bracteatum (H. bracteatum) flower extracts in vitro.
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Article
Open AccessEffects of the myrtle essential oil on the acne skin—clinical trials for Korean women
This study aims to clinically verify the effects of myrtle essential oil, which has non-irritation, non-toxicity, and non-sensitivity characteristics among natural materials, by applying the oil to acne skin o...
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Article
Open AccessProtective effect of protocatechuic acid against inflammatory stress induced in human dermal fibroblasts
Protocatechuic acid (PCA) is an anthocyanin metabolite with a high antioxidant property. It is also known for having anticancer and anti-inflammatory capacities with diverse medicinal activities. As one of the...
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Article
Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite
To find a simple enzymatic strategy for the efficient synthesis of the expensive 5′-hydroxyomeprazole sulfide, a recently identified minor human metabolite, from omeprazole sulfide, which is an inexpensive sub...
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Article
Benzo(a)pyrene represses melanogenesis in B16F10 mouse melanoma cells
Benzo(a)pyrene (BaP) is a chemically based polycyclic aromatic hydrocarbon (PAH) that is readily absorbed by the skin. BaP is metabolized to BaP-diol-epoxide by cytochromes P-450 1A1/2 (CYP1A1/2) and cytochrom...
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Article
Impact of lysophosphatidylcholine on survival and function of UEA-1+acLDL+ endothelial progenitor cells in patients with coronary artery disease
Lysophosphatidylcholine (LPC) generated from oxidized low-density lipoprotein by lipoprotein-associated phospholipase A2 plays a key role in plaque inflammation and vulnerability. Endothelial progenitor cells...