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  1. Article

    Open Access

    Comparison of the expression of cluster of differentiation (CD)39 and CD73 between propofol- and sevoflurane-based anaesthesia during open heart surgery

    High expression of cluster of differentiation (CD)39 and CD73 has cardio-protective effects. We hypothesised that the expression of CD39 and CD73 would differ between propofol- and volatile anaesthetic-based a...

    Chung-Sik Oh, Karam Kim, Woon-Seok Kang, Nam-Sik Woo, Po-Soon Kang in Scientific Reports (2018)

  2. Article

    Open Access

    Epigallocatechin-3-gallate inhibits paclitaxel-induced apoptosis through the alteration of microRNA expression in human dermal papilla cells

    Paclitaxel well known as anti-cancer drug has been shown to cause alopecia in chemotherapy. The paclitaxel chemotherapy-mediated alopecia is induced by apoptotic damage in human dermal papilla (HDP) cells. Epi...

    Shang Hun Shin, Hwa Jun Cha, Karam Kim, In-Sook An, Kyung-Yun Kim in Biomedical Dermatology (2018)

  3. Article

    Open Access

    Sophora japonica extracts accelerates keratinocyte differentiation through miR-181a

    The Sophora japonica extracts contain flavonol triglycoside, isoflavonol, coumarone chromone, saponin, triterpene glucoside, phospholipids, alkaloids, amino acids, polysaccharides, and fatty acids. These componen...

    Karam Kim, Hwa Jun Cha, Dahye Joo, Seong ** Choi, In Sook An in Biomedical Dermatology (2018)

  4. Article

    Open Access

    Annona muricata L. extracts decrease melanogenesis in B16F10 mouse melanoma cells

    Annona muricata (A. muricata) L. (also known as graviola) contains various antioxidants that have beneficial effects on headaches, hypertension, coughs and asthma. A. muricata L. also ...

    Dahye Joo, Seonghee Jeong, Hyun Kyung Lee, Shang Hun Shin in Biomedical Dermatology (2017)

  5. Article

    Open Access

    Coptis chinensis inhibits melanogenesis increasing miR-340-mediated suppression of microphathalmia-associated transcription factor

    Coptis chinensis (C. chinensis) contains various antioxidants, including berberine, epiberberlin, ferulic acid, magnoflorine, palmatine, and worenine, which have antibacterial, anti-in...

    Hyun Kyung Lee, Seonghee Jeong, Shang Hun Shin, Dahye Joo in Biomedical Dermatology (2017)

  6. No Access

    Article

    BIM-based building energy load calculation system for designers

    In addition to the global awareness regarding green buildings, there is growing interest in Building Energy Load Calculation (BELC). The BELC process, however, has several potential problems, including the fac...

    Karam Kim, Jungho Yu in KSCE Journal of Civil Engineering (2016)

  7. No Access

    Article

    Benzo(a)pyrene represses melanogenesis in B16F10 mouse melanoma cells

    Benzo(a)pyrene (BaP) is a chemically based polycyclic aromatic hydrocarbon (PAH) that is readily absorbed by the skin. BaP is metabolized to BaP-diol-epoxide by cytochromes P-450 1A1/2 (CYP1A1/2) and cytochrom...

    Da Hye Joo, Hwa Jun Cha, Karam Kim, Minhee Jung in Molecular & Cellular Toxicology (2015)

  8. No Access

    Article

    Ontological inference of work item based on BIM data

    When engineers prepare a construction cost estimate for budgeting purposes, they use plans, specifications, and available cost data at the completion of the building design phase. They usually take off the qua...

    Seulki Lee, Karam Kim, Jungho Yu in KSCE Journal of Civil Engineering (2015)

  9. Article

    Akt is negatively regulated by the MULAN E3 ligase

    The serine/threonine kinase Akt functions in multiple cellular processes, including cell survival and tumor development. Studies of the mechanisms that negatively regulate Akt have focused on dephosphorylation...

    Seunghee Bae, Sun-Yong Kim, ** Hyuk Jung, Yeongmin Yoon, Hwa Jun Cha in Cell Research (2012)

  10. No Access

    Article

    Resveratrol alters microRNA expression profiles in A549 human non-small cell lung cancer cells

    Resveratrol is a plant phenolic phytoalexin that has been reported to have antitumor properties in several types of cancers. In particular, several studies have suggested that resveratrol exerts antiproliferat...

    Seunghee Bae, Eun-Mee Lee, Hwa Jun Cha, Karam Kim, Yeongmin Yoon in Molecules and Cells (2011)

  11. No Access

    Article

    NGL family PSD-95–interacting adhesion molecules regulate excitatory synapse formation

    Synaptic cell adhesion molecules (CAMs) regulate synapse formation through their trans-synaptic and heterophilic adhesion. Here we show that postsynaptic netrin-G ligand (NGL) CAMs associate with netrin-G CAMs...

    Seho Kim, Alain Burette, Hye Sun Chung, Seok-Kyu Kwon, Jooyeon Woo in Nature Neuroscience (2006)

  12. No Access

    Article

    Functional interaction between human papillomavirus type 18 E2 and poly(ADP-ribose) polymerase 1

    Human papillomavirus E2 protein is a transcription factor of viral gene expression and DNA replication. Here we show that PARP is a positive regulator of the E2 protein of human papillomavirus type 18 (HPV-18)...

    Daeyoup Lee, ** Woo Kim, Karam Kim, Cheol O Joe, Valérie Schreiber in Oncogene (2002)