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Open AccessSoil methane emissions from plain poplar (Populus spp.) plantations with contrasting soil textures
The forest soil methane (CH4) flux exhibits high spatiotemporal variability. Understanding these variations and their driving factors is crucial for accurately assessing the forest CH4 budget. In this study, we m...
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Open AccessComplete telomere-to-telomere genomes uncover virulence evolution conferred by chromosome fusion in oomycete plant pathogens
Variations in chromosome number are occasionally observed among oomycetes, a group that includes many plant pathogens, but the emergence of such variations and their effects on genome and virulence evolution r...
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Open AccessAdverse events reporting of XPO1 inhibitor - selinexor: a real-word analysis from FAERS database
As the world's first oral nuclear export inhibitor, selinexor is increasingly being used in clinical applications for malignant tumors. However, there is no extensive exploration on selinexor's adverse events ...
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Open AccessStructure-based prediction and characterization of photo-crosslinking in native protein–RNA complexes
UV-crosslinking of protein and RNA in direct contacts has been widely used to study protein-RNA complexes while our understanding of the photo-crosslinking mechanisms remains poor. This knowledge gap is due to...
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Open AccessAuthor Correction: Comparison of detection methods for carbonation depth of concrete
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Open AccessPick-up single-cell proteomic analysis for quantifying up to 3000 proteins in a Mammalian cell
The shotgun proteomic analysis is currently the most promising single-cell protein sequencing technology, however its identification level of ~1000 proteins per cell is still insufficient for practical applica...
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Open AccessComparison of detection methods for carbonation depth of concrete
This paper presents comprehensive research of the advantages and applicability of various concrete carbonation detection methods. Employing a combination of Phenolphthalein indicator (PI), Thermogravimetric an...
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Open AccessSex differences in major adverse cardiovascular and cerebrovascular event risk among central retinal artery occlusion patients
To estimate the association between central retinal artery occlusion (CRAO) and major adverse cardiovascular and cerebrovascular events (MACCE), including their clinical characteristics, blood markers, and the...
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Open AccessThe NuRD complex cooperates with SALL4 to orchestrate reprogramming
Cell fate decision involves rewiring of the genome, but remains poorly understood at the chromatin level. Here, we report that chromatin remodeling complex NuRD participates in closing open chromatin in the ea...
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Open AccessA new hybrid algorithm for three-stage gene selection based on whale optimization
In biomedical data mining, the gene dimension is often much larger than the sample size. To solve this problem, we need to use a feature selection algorithm to select feature gene subsets with a strong correla...
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Open AccessEvolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance
It is critical to understand factors associated with nasopharyngeal carcinoma (NPC) metastasis. To track the evolutionary route of metastasis, here we perform an integrative genomic analysis of 163 matched blo...
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Open AccessA novel prognostic model for cutaneous melanoma based on an immune-related gene signature and clinical variables
Abundant evidence has indicated that the prognosis of cutaneous melanoma (CM) patients is highly complicated by the tumour immune microenvironment. We retrieved the clinical data and gene expression data of CM...
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Open AccessN6-methyladenosine RNA modification promotes viral genomic RNA stability and infection
Molecular manipulation of susceptibility (S) genes that are antipodes to resistance (R) genes has been adopted as an alternative strategy for controlling crop diseases. Here, we show the S gene encoding Triticum ...
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Open AccessThe association between altitude and serum folate levels in Tibetan adults on the Tibetan plateau
This study investigated the relationship between residence altitude and serum folate levels in healthy Tibetans living on the Tibetan Plateau. Participants were selected from those who underwent physical exami...
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Open AccessBreast microecology improvement using probiotics following needle aspiration in patients with lactational breast abscess: a multi-center randomized double-blind controlled trial
Although oral probiotics can improve breast microecology and alleviate the inflammatory response, there are no data regarding cases with existing abscesses. We aimed to investigate the effect of Lactobacillus fer...
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Open AccessThe comprehensive detection of miRNA and circRNA in the regulation of intramuscular and subcutaneous adipose tissue of Laiwu pig
circRNAs, as miRNA sponges, participate in many important biological processes. However, it remains unclear whether circRNAs can regulate lipid metabolism. This study aimed to explore the competing endogenouse...
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Open AccessDifferential regulation of mRNAs and lncRNAs related to lipid metabolism in Duolang and Small Tail Han sheep
The function of long non-coding RNA (lncRNA) can be achieved through the regulation of target genes, and the deposition of fat is regulated by lncRNA. Fat has an important effect on meat quality. However, ther...
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Open AccessIdentification of a biomass unaffected pale green mutant gene in Chinese cabbage (Brassica rapa L. ssp. pekinensis)
Chlorophyll (Chl) is an essential component of the photosynthetic apparatus and pigments in plant greening. Leaf color is an important agronomic and commercial trait of Chinese cabbage. In this study, we ident...
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Open AccessWhole-transcriptome analysis and construction of an anther development-related ceRNA network in Chinese cabbage (Brassica campestris L. ssp. pekinensis)
Anther development is precisely regulated by a complex gene network, which is of great significance to plant breeding. However, the molecular mechanism of anther development in Chinese cabbage is unclear. Here...
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Open AccessEndothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration
To control sprouting angiogenesis, endothelial Notch signaling suppresses tip cell formation, migration, and proliferation while promoting barrier formation. Each of these responses may be regulated by distinc...