127 Result(s)

Article

Expression of Concern to: RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial–mesenchymal transition

Chonggao Yin, Hongli Li, Baogang Zhang, Yuqing Liu… in Breast Cancer Research and Treatment (2024)

Article

Tissue factor regulates autophagy in pulmonary artery endothelial cells from chronic thromboembolic pulmonary hypertension rats via the p38 MAPK-FoxO1 pathway

To detect the expression of autophagy components, p38 MAPK (p38) and phosphorylated forkhead box transcription factor O-1 (pFoxO1) in pulmonary vascular endothelial cells of chronic thromboembolic pulmonary hy...

Dawen Wu, Yi Lin, Minxia Yang, Hongli Li, Wenfeng Wang, Qiuxia Wu… in Respiratory Research (2024)

Article

Combinational zimberelimab plus lenvatinib and chemotherapy for alpha-fetoprotein elevated, advanced gastric cancer patients (AFPGC): a phase 1 dose-escalation study

Alpha-fetoprotein elevated gastric cancer (AFPGC) got growing interests for its aggressive nature and unfavorable prognosis. Here, a phase 1 dose escalation study was conducted to evaluate safety and efficacy ...

Ting Deng, Feixue Wang, Le Zhang, Tao Ning, Yansha Sun… in Cancer Immunology, Immunotherapy (2024)

Article

Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic

Quinic acid (QA) and its derivatives have good lipid-lowering and hepatoprotective functions, but their role in atherosclerosis remains unknown. This study attempted to investigate the mechanism of QA on ather...

Qiao **, Chiyuan Zhang, Ran Chen, Lu** Jiang… in Journal of Translational Medicine (2024)

Article

Linc00707 regulates autophagy and promotes the progression of triple negative breast cancer by activation of PI3K/AKT/mTOR pathway

Triple-negative breast cancer (TNBC) is a pathological subtype of breast cancer (BC) with high malignancy, strong invasiveness and poor prognosis. Long non-coding RNA (LncRNA) plays an important role during tu...

Hongli Li, Qinghua Liu, Yaqiong Hu, Chonggao Yin, Yunxiang Zhang… in Cell Death Discovery (2024)

Article

Chemotherapy re-use versus anti-angiogenic monotherapy as the third-line treatment of patients with metastatic colorectal cancer: a real-world cohort study

There are various recommendations for third-line treatment in mCRC, however, there is no consensus on who is more suitable for particular strategy. Chemotherapy re-use in third-line setting is a common option ...

**g**g Duan, Lila Zhu, Yinghui Shi, Weixue Wang, Tongtong Wang, Tao Ning… in BMC Cancer (2024)

Article

Combined score based on plasma fibrinogen and platelet-lymphocyte ratio as a prognostic biomarker in esophageal squamous cell carcinoma

Increasing evidence has showed that inflammatory biomarkers, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and fibrinogen can be used as predictors in the prognosis of esop...

Yuchong Yang, Hui Tan, Yao Lu, Jipeng Mei, Mengqi Zhang, Ming Bai, **a Wang… in BMC Cancer (2024)

Article

Strain ultrasonic elastography imaging features of locally advanced breast cancer: association with response to neoadjuvant chemotherapy and recurrence-free survival

Due to the highly heterogeneity of the breast cancer, it would be desirable to obtain a non-invasive method to early predict the treatment response and survival outcome of the locally advanced breast cancer (L...

Caifeng Wan, Liheng Zhou, Ye **, Fenghua Li, Lin Wang, Wen** Yin… in BMC Medical Imaging (2023)

Article

Retraction Note: Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7

Haiyang Zhang, Ting Deng, Shaohua Ge, Ying Liu, Ming Bai, Kegan Zhu, Qian Fan… in Oncogene (2023)

Article

Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

Citrus fruit has long been considered a healthy food, but its role and detailed mechanism in lifespan extension are not clear. Here, by using the nematode C. elegans, we identified that nomilin, a bitter-taste li...

Shengjie Fan, Yingxuan Yan, Ying **a, Zhenyu Zhou, Lingling Luo… in Nature Communications (2023)

Article

The optimal time of starting adjuvant chemotherapy after curative surgery in patients with colorectal cancer

Postoperative adjuvant chemotherapy (AC) is now well-accepted as standard for high-risk stage II and stage III colorectal cancer (CRC) patients, however the optimal time to initiate AC remains elusive.

Yuchong Yang, Yao Lu, Hui Tan, Ming Bai, **a Wang, Shaohua Ge, Tao Ning… in BMC Cancer (2023)

Article

Anti-Alzheimers molecular mechanism of icariin: insights from gut microbiota, metabolomics, and network pharmacology

Icariin (ICA), an active ingredient extracted from Epimedium species, has shown promising results in the treatment of Alzheimer's disease (AD), although its potential therapeutic mechanism remains largely unknown...

Yuqing Liu, Hongli Li, **aowei Wang, Jianhua Huang… in Journal of Translational Medicine (2023)

Article

The melanocortin action is biased toward protection from weight loss in mice

The melanocortin action is well perceived for its ability to regulate body weight bidirectionally with its gain of function reducing body weight and loss of function promoting obesity. However, this notion can...

Hongli Li, Yuanzhong Xu, Yanyan Jiang, Zhiying Jiang… in Nature Communications (2023)