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  1. Article

    Open Access

    A newly developed deep learning-based system for automatic detection and classification of small bowel lesions during double-balloon enteroscopy examination

    Double-balloon enteroscopy (DBE) is a standard method for diagnosing and treating small bowel disease. However, DBE may yield false-negative results due to oversight or inexperience. We aim to develop a comput...

    Yijie Zhu, **aoguang Lyu, **ao Tao, Lianlian Wu, Anning Yin in BMC Gastroenterology (2024)

  2. No Access

    Article

    Exploring the challenge of early gastric cancer diagnostic AI system face in multiple centers and its potential solutions

    Artificial intelligence (AI) performed variously among test sets with different diversity due to sample selection bias, which can be stumbling block for AI applications. We previously tested AI named ENDOANGEL...

    Zehua Dong, **ao Tao, Hongliu Du, Junxiao Wang, Li Huang in Journal of Gastroenterology (2023)

  3. No Access

    Article

    Failure Analysis of Pipeline Corrosion Perforation in a Gas Mine

    Pipe with an outer diameter of 159 mm and a design wall thickness of 5 mm in a gas mine was corroded and perforated, resulting in gas collection interruption and significant economic loss. The maximum corrosio...

    Jian Gao, **aobin Liu, Liang Zhang, Zixia Hu in Journal of Failure Analysis and Prevention (2023)

  4. Article

    Open Access

    Publisher Correction: Explainable artificial intelligence incorporated with domain knowledge diagnosing early gastric neoplasms under white light endoscopy

    Zehua Dong, Junxiao Wang, Yanxia Li, Yunchao Deng, Wei Zhou in npj Digital Medicine (2023)

  5. Article

    Open Access

    The effectiveness of a computer-aided system in improving the detection rate of gastric neoplasm and early gastric cancer: study protocol for a multi-centre, randomized controlled trial

    This protocol is for a multi-centre randomised controlled trial to determine whether the computer-aided system ENDOANGEL-GC improves the detection rates of gastric neoplasms and early gastric cancer (EGC) in r...

    Zehua Dong, Yijie Zhu, Hongliu Du, Junxiao Wang, **aoquan Zeng, **ao Tao in Trials (2023)

  6. Article

    Open Access

    Explainable artificial intelligence incorporated with domain knowledge diagnosing early gastric neoplasms under white light endoscopy

    White light endoscopy is the most pivotal tool for detecting early gastric neoplasms. Previous artificial intelligence (AI) systems were primarily unexplainable, affecting their clinical credibility and accept...

    Zehua Dong, Junxiao Wang, Yanxia Li, Yunchao Deng, Wei Zhou in npj Digital Medicine (2023)

  7. No Access

    Article

    Targeted labeling with tissue marking dyes guided by magnifying endoscopy of endoscopic submucosal dissection specimen improves the accuracy of endoscopic and histopathological diagnosis of early gastric cancer: a before–after study

    Although histopathological evaluation after endoscopic submucosal dissection (ESD) is critical to assess the accuracy of endoscopic diagnosis, it is still challenging to perform precise endoscopic to pathologi...

    **g Wang, Zhi Zeng, Shiying Zhang, Jian Kang, **aoda Jiang, Xu Huang in Surgical Endoscopy (2023)

  8. Article

    A deep-learning based system using multi-modal data for diagnosing gastric neoplasms in real-time (with video)

    White light (WL) and weak-magnifying (WM) endoscopy are both important methods for diagnosing gastric neoplasms. This study constructed a deep-learning system named ENDOANGEL-MM (multi-modal) aimed at real-tim...

    Hongliu Du, Zehua Dong, Lianlian Wu, Yanxia Li, Jun Liu, Chaijie Luo in Gastric Cancer (2023)

  9. Article

    Open Access

    An interpretable artificial intelligence system for detecting risk factors of gastroesophageal variceal bleeding

    Bleeding risk factors for gastroesophageal varices (GEV) detected by endoscopy in cirrhotic patients determine the prophylactical treatment patients will undergo in the following 2 years. We propose a methodol...

    **g Wang, Zhengqiang Wang, Mingkai Chen, Yong **ao, Shi Chen in npj Digital Medicine (2022)

  10. Article

    Open Access

    FIT-based risk-stratification model effectively screens colorectal neoplasia and early-onset colorectal cancer in Chinese population: a nationwide multicenter prospective study

    No fully validated risk-stratification strategies have been established in China where colonoscopies resources are limited. We aimed to develop and validate a fecal immunochemical test (FIT)-based risk-stratif...

    Shengbing Zhao, Shuling Wang, Peng Pan, Tian **a in Journal of Hematology & Oncology (2022)

  11. Article

    Correction to: Propionibacterium acnes overabundance in gastric cancer promote M2 polarization of macrophages via a TLR4/PI3K/Akt signaling

    Qing Li, Wei Wu, Dexin Gong, Renduo Shang, **g Wang, Honggang Yu in Gastric Cancer (2022)

  12. Article

    Open Access

    Evaluating the effect of an artificial intelligence system on the anesthesia quality control during gastrointestinal endoscopy with sedation: a randomized controlled trial

    Sedative gastrointestinal endoscopy is extensively used worldwide. An appropriate degree of sedation leads to more acceptability and satisfaction. Artificial intelligence has rapidly developed in the field of ...

    Cheng Xu, Yijie Zhu, Lianlian Wu, Honggang Yu, Jun Liu, Fang Zhou in BMC Anesthesiology (2022)

  13. Article

    Propionibacterium acnes overabundance in gastric cancer promote M2 polarization of macrophages via a TLR4/PI3K/Akt signaling

    Eradication of Helicobacter pylori (H. pylori) could not completely prevent the progression of gastric cancer (GC), suggesting that non-H. pylori bacteria may participate in the carcinogenesis of GC. The dysbiosi...

    Qing Li, Wei Wu, Dexin Gong, Renduo Shang, **g Wang, Honggang Yu in Gastric Cancer (2021)

  14. Article

    Gastrointestinal Symptoms Onset in COVID-19 Patients in Wuhan, China

    Early detection is critical in limiting the spread of 2019 novel coronavirus (COVID-19). Although previous data revealed characteristics of GI symptoms in COVID-19, for patients with only GI symptoms onset, th...

    ** An, Hongbin Chen, Haixia Ren, Juan Su, Mengyao Ji in Digestive Diseases and Sciences (2021)

  15. Article

    Open Access

    WNT4 secreted by tumor tissues promotes tumor progression in colorectal cancer by activation of the Wnt/β-catenin signalling pathway

    Wingless and Int-related protein (Wnt) ligands are aberrantly expressed in patients with colorectal cancer (CRC). However, the aberrant level of Wnt ligands in serum have not been explored. Here, we aimed to i...

    Dongmei Yang, Qing Li, Renduo Shang in Journal of Experimental & Clinical Cancer … (2020)

  16. Article

    Open Access

    Deep learning-based model for detecting 2019 novel coronavirus pneumonia on high-resolution computed tomography

    Computed tomography (CT) is the preferred imaging method for diagnosing 2019 novel coronavirus (COVID19) pneumonia. We aimed to construct a system based on deep learning for detecting COVID-19 pneumonia on hig...

    Jun Chen, Lianlian Wu, Jun Zhang, Liang Zhang, Dexin Gong, Yilin Zhao in Scientific Reports (2020)

  17. No Access

    Article

    CCL19 suppresses gastric cancer cell proliferation, migration, and invasion through the CCL19/CCR7/AIM2 pathway

    Absent in melanoma 2 (AIM2) has been reported to be an important inflammasome component that exerts tumor suppression in several tumors. However, whether CCL19/CCR7/AIM2 is involved in the progression of GC st...

    Rui Zhou, Jun Sun, Chun** He, Chao Huang, Honggang Yu in Human Cell (2020)

  18. Article

    A deep learning method for delineating early gastric cancer resection margin under chromoendoscopy and white light endoscopy

    Accurate delineation of cancer margins is critical for endoscopic curative resection. This study aimed to train and validate real-time fully convolutional networks for delineating the resection margin of early...

    ** An, Dongmei Yang, **g Wang, Lianlian Wu, Jie Zhou, Zhi Zeng in Gastric Cancer (2020)

  19. Article

    Open Access

    Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13–RhoA–ROCK signaling pathway

    The mechanism by which gastrin promotes pancreatic cancer cell metastasis is unclear. The process of directing polarized cancer cells toward the extracellular matrix is principally required for invasion and di...

    Ganggang Mu, Qianshan Ding, Hongyan Li, Li Zhang in Experimental & Molecular Medicine (2018)

  20. No Access

    Article

    Reanalysis of microRNA expression profiles identifies novel biomarkers for hepatocellular carcinoma prognosis

    The aim of our study is to identify microRNAs (miRNAs) that have significance in the prognosis and pathogenesis of hepatocellular carcinoma (HCC). The miRNAs differentially expressed in HCC were examined by us...

    Zhengqiang Wang, Qianshan Ding, Yanxia Li, Qingqing Liu, Wei Wu, Lu Wu in Tumor Biology (2016)

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