79 Result(s)
within
Hong**g Cheng
Biomedicine
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Article
Breast Cancer and Dietary Factors in Taiwanese Women
To examine the effect of the consumption of dietary factors on the risk of breast cancer in a case–control study in Taiwan.
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Article
Capillary gas chromatographic determination of dimethachlon residues in fresh tobacco leaves and cut-tobacco
Simple procedures for extraction and chromatographic determination of dimethachlon residues in fresh tobacco leaves and cut-tobacco are described. The determination was carried out by capillary gas chromatogra...
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Article
Open AccessId1 induces apoptosis through inhibition of RORgammat expression
Basic helix-loop-helix E proteins are transcription factors that play crucial roles in T cell development by controlling thymocyte proliferation, differentiation and survival. E protein functions can be repres...
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Article
Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase
To investigate whether resveratrol (RSV) can improve non-alcoholic fatty liver disease (NAFLD) and to find the possible mechanism.
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Article
A large novel deletion in the APC promoter region causes gene silencing and leads to classical familial adenomatous polyposis in a Manitoba Mennonite kindred
Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by the inheritance of germline mutations in the APC tumour suppressor gene. The vast majority of these are nonsense and frameshift mut...
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Article
P53 polymorphism and lung cancer susceptibility: a pooled analysis of 32 case–control studies
To explore the real association between p53 codon 72 polymorphism and lung cancer risk, a pooled analysis of 32 case–control studies involving 19,255 subjects was conducted. When all 32 studies were pooled into t...
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Article
Gemcitabine combined with gum mastic causes potent growth inhibition and apoptosis of pancreatic cancer cells
To investigate the antiproliferative and apoptotic effects of gemcitabine combined with gum mastic and the underlying mechanisms in human pancreatic cancer cell lines.
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Article
Open AccessThe common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Bei**g, China
Previous genome-wide association studies for type 2 diabetes susceptibility genes have confirmed that a common variant, rs9939609, in the fat mass and obesity associated (FTO) gene region is associated with body ...
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Article
Open AccessModulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke
The relationship between functional improvements in ischemic rats given a neural stem cell (NSC) transplant and the modulation of the class I major histocompatibility complex (MHC) mediated by NSC-derived neur...
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Article
Urinary trypsin inhibitor attenuates lipopolysaccharide-induced acute lung injury by blocking the activation of p38 mitogen-activated protein kinase
To investigate the protective effect of urinary trypsin inhibitor (UTI) in a rat model of lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the underlying molecular mechanism.
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Article
Open AccessDetection of HBV Genotypes of Tumor Tissues and Serum by A Fluorescence Polarization Assay in North-Western China's Hepatocellular Carcinoma Patients
The understanding of the distribution of hepatitis B virus genotypes and the occult hepatitis B virus infection in hepatocellular carcinoma may shed light into the prevention and treatment of hepatocellular ca...
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Article
Synthesis and cytotoxicity of novel chrysin derivatives
A series of chrysin derivatives 8a–8v were prepared and tested in vitro against HCT-116 (human colon cancer cell line), Hela (human cervical carcinoma cell line), DU-145 (human prostate cell line), K562 (human...
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Article
Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nan**g
Berries are a good source of natural antioxidants. In the present study, the total antioxidant capacity and phenolic composition of three berry fruits (blueberry, blackberry, and strawberry) cultivated in Nanj...
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Open AccessTreatment of one case of cerebral palsy combined with posterior visual pathway injury using autologous bone marrow mesenchymal stem cells
Cerebral palsy is currently one of the major diseases that cause severe paralysis of the nervous system in children; approximately 9–30% of cerebral palsy patients are also visually impaired, for which no effe...
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Article
IDO-Competent-DCs Induced by IFN-γ Attenuate Acute Rejection in rat Liver Transplantation
We established a stable rat model of liver transplantation using Sprague-Dawley rats and Wistar rats in order to investigate the role of the IDO gene in acute rejection after rat liver transplantation.
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Article
The Lupus-derived Anti-double-stranded DNA IgG Contributes to Myofibroblast-like Phenotype in Mesangial Cells
Anti–double-stranded DNA (dsDNA) antibodies have been indicated to play a major role in the pathogenesis of lupus nephritis (LN), which is characterized by mesangial alterations, including phenotypic changes. ...
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Article
Quantitative assessment of the influence of cytochrome P450 2C19 gene polymorphisms and digestive tract cancer risk
Cytochrome P450 (CYP) 2C19 metabolizes many promutagens and procarcinogens to biologically active metabolites, which strongly promote proliferation of cancer cells in vitro and in vivo. The CYP2C19 gene exhibi...
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Article
Common genetic variants associated with lipid profiles in a Chinese pediatric population
Genome-wide association (GWA) studies have identified many candidate genes that are associated with blood lipid and lipoprotein concentrations. In this study, we want to know whether the results from European ...
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Article
Open AccessComparative analysis of curative effect of CT-guided stem cell transplantation and open surgical transplantation for sequelae of spinal cord injury
This study compared the clinical efficacies, advantages and disadvantages of two transplantation approaches for treating spinal cord injury: open surgical exploration combined with local stem cell transplantat...
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Article
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias
In heart muscle cells, sarcoplasmic reticulum calcium overload leads to spontaneous calcium waves that can cause arrhythmias and sudden cardiac death. S.R. Wayne Chen and his colleagues now detail the molecula...
