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Article
Nuclear morphological atypia in biopsy accurately reflects the prognosis of myxoid liposarcoma
Currently, it is difficult to predict the prognosis of myxoid liposarcoma (MLS) in biopsy specimens. In this study, we determined whether nuclear morphology may be used to predict the prognosis of MLS in prima...
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Article
Open AccessThe contributions of deleterious rare alleles in NLRP12 and inflammasome-related genes to polymyalgia rheumatica
Polymyalgia rheumatica (PMR) is a chronic inflammatory disease characterized by arthralgia and myalgia of the shoulder and hip girdles, and fever. PMR is linked to autoimmune diseases and autoinflammatory diso...
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Article
Open AccessAnalysis of proteins released from osteoarthritic cartilage by compressive loading
In osteoarthritis (OA), synovial pathology may be induced by proteins released from degenerated cartilage. This study was conducted to identify the proteins released from OA cartilage. OA cartilage was obtaine...
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Article
Effect of the number of cycles of docetaxel + S-1 therapy on long-term survival in adjuvant chemotherapy for stage III gastric cancer. A pooled analysis of the OGSG0604 and OGSG1002 trials
S-1 plus docetaxel (DS) therapy followed by S-1 is the standard of care in Japan in postoperative adjuvant chemotherapy for stage III gastric cancer, but long-term survival and the number of DS cycles required...
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Article
Restoration of lymph flow by flap transfer can prevent severe lower extremity lymphedema after inguino-pelvic lymphadenectomy
Severe lymphedema is difficult to treat because of the associated extensive scar formation. Therefore, preventing scar formation might alleviate the severity of lymphedema following lymphadenectomy. In this st...
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Article
Open AccessPredisposition of HLA-DRB1*04:01/*15 heterozygous genotypes to Japanese mixed connective tissue disease
Mixed connective tissue disease (MCTD) is a rare systemic autoimmune disease characterized by the production of anti-U1 ribonucleoprotein antibodies and systemic symptoms similar to those of some other autoimm...
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Article
Open AccessSerum rheumatoid factor IgA, anti-citrullinated peptide antibodies with secretory components, and anti-carbamylated protein antibodies associate with interstitial lung disease in rheumatoid arthritis
Rheumatoid arthritis (RA) is often complicated with chronic lung diseases (CLD), including interstitial lung disease (ILD) and airway disease, which occur as extra-articular manifestations. CLD in RA have been...
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Article
Clinicopathological and prognostic significance of H3K27 methylation status in malignant peripheral nerve sheath tumor: correlation with skeletal muscle differentiation
Malignant peripheral nerve sheath tumor (MPNST) is a very aggressive peripheral nerve sheath-derived sarcoma, which is one of the most difficult tumors to diagnose due to its wide spectrum of histological find...
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Article
Open AccessThe attenuation of insulin-like growth factor signaling may be responsible for relative reduction in matrix synthesis in degenerated areas of osteoarthritic cartilage
In osteoarthritis (OA), cartilage matrix is lost gradually despite enhanced matrix synthesis by chondrocytes. This paradox may be explained, at least partly, by reduced chondrocyte anabolism in degenerated are...
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Article
Open AccessIntraoperative collection of autologous platelet-rich plasma from the cardiopulmonary bypass circuit upon initiation of extracorporeal circulation
The aim of this study is to evaluate the possibility of the autologous platelet-rich plasma (PRP) collection from the cardiopulmonary bypass (CPB) circuit and to evaluate its effect on the aggregative function.
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Article
Open AccessGenetic risk factors for autoimmune hepatitis: implications for phenotypic heterogeneity and biomarkers for drug response
Autoimmune hepatitis (AIH) is a rare chronic progressive liver disease with autoimmune features. It mainly affects middle-aged women. AIH is occasionally complicated with liver cirrhosis that worsens the progn...
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Article
Controlling lymph node micrometastases by neoadjuvant chemotherapy affects the prognosis in advanced esophageal squamous cell carcinoma
The purpose of this study is to determine the clinical significance of micrometastases after neoadjuvant chemotherapy (NAC) and the difference in controlling micrometastases using different NAC regimens in res...
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Chapter and Conference Paper
Study on the Impact of Learning About Information Security Measures on Mental Models: Applying Cybersecurity Frameworks to Self-learning Materials
The shortage of information-security workers is a problem. Appropriate mental models are considered important to encourage learners to appropriately plan, understand, and act on security measures. We aim to cr...
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Article
A surgical case of triple valve replacement for triple valve endocarditis with multiple vegetations
A 68-year-old man with cerebral infarction and right hemiplegia was diagnosed with active infective endocarditis, and multiple large vegetations and more than moderate valve regurgitation by three different va...
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Article
Local administration of the powder minocycline during surgical intervention for active infective endocarditis
We retrospectively assessed the initial clinical impact of the locally administered bacteriostatic antibiotic, powder minocycline, during surgery for active infective endocarditis (AIE).
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Article
Surgical management of large undifferentiated cardiac sarcoma involving the right ventricle to pulmonary trunk
A large intra-cardiac tumor from the right ventricle to pulmonary trunk was detected by contrast-enhanced computed tomography and transthoracic echocardiography in a 59-year-old woman with progressive dyspnea ...
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Article
Angiographic appearance of patent saphenous vein grafts more than 25 years after coronary artery bypass grafting
Nine patients with ten angiographical patent saphenous vein grafts (SVG) more than 25 years after coronary artery bypass grafting (CABG) at Kawasaki Medical School Hospital between 1976 and 1992 were reviewed....
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Chapter
Wireless Backhaul Technology in Wireless Sensor Networks: Basic Framework and Applications
Setting up a wireless sensor network (WSN) requires installing multiple sensor nodes and gateways. Installation costs of existing WSNs tend to be high when the sensing areas become wide, because all of the sen...
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Chapter and Conference Paper
A Route Evaluation Method Considering the Subjective Evaluation on Walkability, Safety, and Pleasantness by Elderly Pedestrians
To improve the quality of life (QOL) of elderly people, we propose a route planning method considering the subjective evaluation on walkability, safety, and pleasantness of the users. By using this method, it ...
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Article
Combination laser therapy as a non-surgical method for treating congenital melanocytic nevi from cosmetically sensitive locations on the body
