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  1. No Access

    Article

    CD30: from basic research to cancer therapy

    The FDA recently approved an agonistic anti-CD30 drug conjugate, Brentuximab vedotin, for the treatment for CD30-positive lymphomas. The potent clinical activity of Brentuximab vedotin in Hodgkin’s lymphoma a...

    Hiromi Muta, Eckhard R. Podack in Immunologic Research (2013)

  2. No Access

    Article

    CD30 Ligand/CD30 Interaction Is Involved in Pathogenesis of Inflammatory Bowel Disease

    Although CD30 has long been recognized as an important marker in many lymphomas of diverse origin, and as an activation molecule on B and T cells, its primary function has remained obscure. Soluble CD30 (sCD30...

    Shinichi Somada, Hiromi Muta, Kazuhiko Nakamura, Xun Sun… in Digestive Diseases and Sciences (2012)

  3. No Access

    Article

    Warfarin Therapy for Giant Aneurysm Prevents Myocardial Infarction in Kawasaki Disease

    We retrospectively investigated the effect of warfarin therapy in improving the clinical outcome of Kawasaki disease (KD) patients with giant coronary aneurysms (GAs). We followed 2350 KD patients from 1973 to...

    Yoko Sugahara, Masahiro Ishii, Hiromi Muta, Motofumi Iemura… in Pediatric Cardiology (2008)

  4. No Access

    Article

    Gastric emptying in diabetic patients by the 13C-octanoic acid breath test: role of insulin in gastric motility

    Impairment of gastric emptying is well recognized in patients with diabetes mellitus (DM), especially long-standing insulin-dependent diabetes mellitus (IDDM). The aim of this study was to evaluate the cause o...

    Masahiro Matsumoto, Rie Yoshimura, Hirotada Akiho… in Journal of Gastroenterology (2007)

  5. Article

    The Effectiveness and Safety of Early Intravenous Immune Globulin Treatment for Kawasaki Disease

    The diagnosis of Kawasaki disease (KD) is based on 5 characteristic clinical symptoms with fever persisting at least 5 days. Recently, early diagnosis and early intravenous immune globulin (IVIG) treatment are...

    Yoko Sugahara, Masahiro Ishii, Hiromi Muta, Jun Furui, Wakako Himeno… in Pediatric Research (2003)

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  6. Article

    Quantitative Evaluation of Severity of Coronary Artery Damage in Kawasaki Disease: Ultrasonic Tissue Characterization Method and Vascular Endothelial Growth Factor

    We evaluated the severity of coronary artery (CA) damage quantitatively by an ultrasonic tissue characterization (UTC) method and the plasma levels of vascular endothelial growth factor (VEGF) in patients (pts...

    Jun Furui, Masahiro Ishii, Yoko Sugahara, Wakako Himeno, Hiromi Muta… in Pediatric Research (2003)

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  7. Article

    Assessment of the Ability of Intravenous Myocardial Contrast Echocardiography to Identify Perfusion Abnormalities in Patients with Kawasaki Disease

    Patients (pts) with Kawasaki disease (KD) who develop myocardial infarction are usually asymptomatic before the event; thus, it is crucial that pts at risk be identified. The aim of our study was to assess the...

    Masahiro Ishii, Wakako Himeno, Yoko Sugahara, Motofumi Iemura… in Pediatric Research (2003)

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  8. Article

    Vascular Wall Morphology and Vascular Elasticity of Coronary Aneurysms in Long-term after Kawasaki Disease: Intravascular Ultrasound Study

    The coronary artery (CA) lesion in Kawasaki disease (KD) may be a long term coronary risk factor. We examined the CA wall morphology and elasticity of CA itself using intravascular ultrasound (IVUS) imaging in...

    Masahiro Ishii, Motofumi Iemura, Yoko Sugahara, Kanoko Hashino… in Pediatric Research (2003)

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  9. Article

    Randomized Controlled Study of Intravenous Gamma-globulin Products in Treatment of Kawasaki Disease

    Background: The efficacy of high-dose intravenous gamma-globulin (IVGG) treatment in Kawasaki disease (KD) is well known. But it is unclear whether the IVGG products manufactured by various companies are equally ...

    Hiromi Muta, Masahiro Ishii, Yoko Sugahara, Teiji Akagi… in Pediatric Research (2003)

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