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Article
Open AccessRemoval performance of pre- and post-dilution online hemodiafiltration using identical hemodiafilters in the same patients
Online hemodiafiltration (OHDF) for renal replacement therapy has two modes: pre- (pre-OHDF) and post-dilution OHDF (post-OHDF). To elucidate the precise differences between the two modes, a clinical study was...
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Chapter and Conference Paper
Effect of Laser Heat Treatment and Nitrogen Content in Shielding Gas on Precipitation of Widmanstätten Austenite in Lap Laser Welds of Duplex Stainless Steels
Duplex stainless steel attracts attention because of its excellent mechanical properties and corrosion resistance, which characterize both the ferrite and the austenite phases. However, it’s well known that th...
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Chapter and Conference Paper
Effect of Nitrogen on Weldability and the Microstructure in Laser Beam Welding of Duplex Stainless Steel
Due to ’ contents in welds , their mechanical properties and corrosion resistance should be remarkably degraded from base metals’ ones. It is reported that both the precipitation and growth of the in the w...
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Article
Open AccessIdentifying Blood Transcriptome Biomarkers of Alzheimer’s Disease Using Transgenic Mice
The testing of pathological biomarkers of Alzheimer’s disease (AD), such as amyloid beta and tau, is time-consuming, expensive, and invasive. Here, we used 3xTg-AD mice to identify and validate putative novel ...
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Chapter and Conference Paper
Effects of Welding Conditions and Post-Weld Heat Treatment on Precipitation of Widmanstätten-Austenite of Duplex Stainless Steels
In the case of welding for , the welds change in the morphology and ferrite/austenite due to the welding conditions and the alloy composition of the material itself. Especially when using the what has the...
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Article
Influence of albumin leakage on glycated albumin in patients with type 2 diabetes undergoing hemodialysis
Glycated albumin (GA) is recommended as a better glycemic indicator than HbA1c in patients undergoing hemodialysis, because the red blood cell lifespan is generally faster than that in normal subjects. However...
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Article
Open AccessInfluence of seasonal changes on disease activity and distribution of affected joints in rheumatoid arthritis
Previous studies suggest that RA activity is sensitive to seasonal changes. This study explored the influence of season on RA activity, particularly the distribution of affected joints, using a nationwide data...
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Article
AS1387392, a novel immunosuppressive cyclic tetrapeptide compound with inhibitory activity against mammalian histone deacetylase
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Article
Open AccessBenign giant mediastinal schwannoma presenting as cardiac tamponade in a woman: a case report
Mediastinal schwannomas are typically benign and asymptomatic, and generally present no immediate risks. We encountered a rare case of a giant benign posterior mediastinal schwannoma, complicated by life-threa...
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Article
AS1387392, a novel immunosuppressive cyclic tetrapeptide compound with inhibitory activity against mammalian histone deacetylase
The novel immunosuppressant AS1387392 has been isolated from Acremonium sp. No. 27082. This compound showed a strong inhibitory effect against mammalian histone deacetylase and T-cell proliferation. Further, AS13...
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Article
Bioconversion of AS1387392: bioconversion studies involving Amycolatopsis azurea JCM 3275
We screened actinomycetes capable of converting AS1387392 to AS1429716 and identified those strains capable of hydroxylation. Amycolatopsis azurea JCM 3275 was found to be a particularly efficient strain, capable...
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Article
Peptide Thioester Synthesis via an Auxiliary-Mediated N–S Acyl Shift Reaction in Solution
The 4,5-dimethoxy-2-mercaptobenzyl (Dmmb) group attached to a main chain amide in a peptide is easily transformed into an S-peptide via an intramolecular N–S acyl shift reaction under acidic conditions, and the S
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Chapter
Production and Transport of Ozone in Local Flows over Central Japan-Comparison of Numerical Calculation with Airborne Observation—
The Central Japan has notable topographical features such that high mountains of the Japanese Alps exist at its center, large plains extend in its coastal area, and it is bounded with complex coast lines at th...
