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Open AccessEvaluation of a quantitative PCR-based method for chimerism analysis of Japanese donor/recipient pairs
Chimerism analysis is a surrogate indicator of graft rejection or relapse after allogeneic hematopoietic stem cell transplantation (HSCT). Although short tandem repeat PCR (STR-PCR) is the usual method, limite...
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Article
Effects of second transplantation with T-cell-replete haploidentical graft using low-dose anti-thymocyte globulin on long-term overall survival in pediatric patients with relapse of leukemia after first allogeneic transplantation
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the preferred treatment for children with high-risk hematologic malignancies, but post-allo-HSCT relapse has a poor prognosis and limited treat...
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Article
A retrospective analysis of azacitidine treatment for juvenile myelomonocytic leukemia
Juvenile myelomonocytic leukemia (JMML) is a pediatric hematological malignancy with a poor prognosis. Although several case series have been published describing hematological and molecular responses to azaci...
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Article
Open AccessAlloantigen-activated (AAA) CD4+ T cells reinvigorate host endogenous T cell immunity to eliminate pre-established tumors in mice
Cancer vaccines that induce endogenous antitumor immunity represent an ideal strategy to overcome intractable cancers. However, doing this against a pre-established cancer using autologous immune cells has pro...
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Long-term outcome in patients with Fanconi anemia who received hematopoietic stem cell transplantation: a retrospective nationwide analysis
We retrospectively analyzed nationwide records of 163 Fanconi anemia (FA) patients [aplastic anemia (AA), n = 118; myelodysplastic syndrome (MDS), n = 30; acute leukemia, n = 15] who underwent first allogeneic he...
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Article
Sampled-data output regulation of unstable well-posed infinite-dimensional systems with constant reference and disturbance signals
We study the sample-data control problem of output tracking and disturbance rejection for unstable well-posed linear infinite-dimensional systems with constant reference and disturbance signals. We obtain a su...
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Article
Boundary stabilization of first-order hyperbolic equations with input delay
This paper is concerned with the boundary stabilization problem of first-order hyperbolic equations with input delay. In our previous work, the same problem for parabolic equations with input delay was address...
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Article
Open AccessSuvorexant (Belsomra® Tablets 10, 15, and 20 mg): Japanese Drug-Use Results Survey
We report on the results of a Japanese postmarketing drug-use survey of suvorexant (Belsomra®) tablets.
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Article
Predictors for linear parabolic systems with input delay
In this paper, we study the problem of stabilizing one-dimensional parabolic systems with input delay. Especially, we consider the case of “distributed control”. The purpose is to derive the stabilizing contro...
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Article
T-cell-replete haploidentical stem cell transplantation using low-dose antithymocyte globulin in children with relapsed or refractory acute leukemia
We evaluated the efficacy and toxicity of T-cell-replete haploidentical stem cell transplantation (TCR-haploSCT) using low-dose antithymocyte globulin (ATG) in children with refractory/relapsed (R/R) acute leu...
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Article
Open AccessUsefulness of fluorodeoxyglucose positron emission tomography/computed tomography for detection of a neuroblastic nodule in a ganglioneuroblastoma: a case report
Ganglioneuroblastoma, nodular is defined as a composite tumor of biologically distinct clones. The peripheral neuroblastic tumors in this category are characterized by the presence of grossly visible neuroblas...
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Open AccessApplication of the backstep** method to the prediction of increase or decrease of infected population
In mathematical epidemiology, age-structured epidemic models have usually been formulated as the boundary-value problems of the partial differential equations. On the other hand, in engineering, the backsteppi...
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Long-term remission of HSCT-related NS after a second allogenic stem cell transplant
Hematopoietic stem cell transplantation (HSCT)-related nephrotic syndrome (NS) is a rare event and has been described as a clinical form of chronic graft-versus-host disease (GVHD). Although immunological mech...
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Impaired regulatory T cell reconstitution in patients with acute graft-versus-host disease and cytomegalovirus infection after allogeneic bone marrow transplantation
To elucidate the correlation between regulatory T cells (Tregs) and acute graft-versus-host disease (aGVHD) or cytomegalovirus infection following allogeneic bone marrow transplantation (allo-BMT), we evaluate...
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Article
Central neurogenic hyperventilation treated with intravenous fentanyl followed by transdermal application
Central neurogenic hyperventilation (CNH) is a rare clinical condition that is sometimes difficult to treat. We report a 51-year-old female patient who was successfully treated with intravenous fentanyl follow...
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Article
Stabilization of a flexible cable with two rigid loads
In this paper, we study the stabilization problem of a flexible cable with two rigid loads which is described by two kinds of hyperbolic equations. From the engineering point of view, the model can be regarded...
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Article
Collection by a simple bag method and the function of granulocytes in granulocyte transfusion
Granulocyte transfusion is effective for treating some intractable infections. We have recently developed a simple bag method for collecting granulocytes without using apheresis. A recombinant human granulocyt...
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Pneumothorax of undetermined etiology occurring during general anesthesia