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Article
Open AccessBody-part specificity for learning of multiple prior distributions in human coincidence timing
During timing tasks, the brain learns the statistical distribution of target intervals and integrates this prior knowledge with sensory inputs to optimise task performance. Daily events can have different temp...
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Article
Open AccessSafety and Effectiveness of Molnupiravir in Japanese Patients with COVID-19: Final Report of Post-marketing Surveillance in Japan
Molnupiravir is an orally available prodrug of N-hydroxycytidine that received special approval for emergency treatment of coronavirus disease 2019 (COVID-19) in Japan in December 2021 and full approval in April ...
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Article
Open AccessWeakened Bayesian Calibration for Tactile Temporal Order Judgment in Individuals with Higher Autistic Traits
Previous psychophysical studies reported a positive aftereffect in tactile temporal order judgments, which can be explained by the Bayesian estimation model (‘Bayesian calibration’). We investigated the relati...
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Article
Open AccessAcquisition of novel ball-related skills associated with sports experience
Some individuals can quickly acquire novel motor skills, while others take longer. This study aimed to investigate the relationships between neurophysiological state, sports experience, and novel ball-related ...
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Article
Cerebral venous sinus thrombosis in child with antithrombin deficiency and novel SERPINC1 variant
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Article
Open AccessPLEKHA5 regulates the survival and peritoneal dissemination of diffuse-type gastric carcinoma cells with Met gene amplification
Met gene amplification has been found in a subset of malignant carcinomas, including diffuse-type gastric carcinoma (DGC), which has a poor prognosis owing to rapid infiltrative invasion and frequent peritonea...
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Article
Drug screening with a novel tumor-derived cell line identified alternative therapeutic options for patients with atypical teratoid/rhabdoid tumor
Atypical teratoid/rhabdoid tumor (AT/RT) is a rare intracranial tumor occurring predominantly in young children. The prognosis is poor, and no effective treatment is currently available. To develop novel effec...
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Chapter and Conference Paper
Deformation Behavior in Magnetic Pressure Parallel Seam Welding
Magnetic pressure seam welding has attracted attention as a new joining method . Magnetic pressure seam welding is a collision welding process for producing metallic bonds of similar and dissimilar materials,...
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Article
Open AccessPharmacokinetic–pharmacodynamic modelling of the hypoglycaemic effect of pulsatile administration of human insulin in rats
The relationship between the plasma insulin (INS) concentration–time course and plasma glucose concentration–time course during and after pulsatile INS administration to rats was characterized using a pharmaco...
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Article
Open AccessCharacteristics of pediatric adverse drug reaction reports in the Japanese Adverse Drug Event Report Database
There are no reports on investigations of the characteristics of adverse drug reaction (ADR) reports for pediatric patients in the Japanese Adverse Drug Event Report database (JADER) and the utility of databas...
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Article
Open AccessEffects of synchronised engine sound and vibration presentation on visually induced motion sickness
Driving simulator usage is often accompanied by motion sickness, and techniques for its prevention are not yet established. To reduce visually induced motion sickness (VIMS), we investigated the effects of syn...
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Article
The quality assessment of the Japanese Adverse Drug Event Report database using vigiGrade
Background The quality of adverse drug reaction reports can have a strong influence on the causality assessment or the detection of safety signals. Various methods have been used to evaluate the quality of advers...
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Article
Open Access5-Nitrouracil stabilizes the plasma concentration values of 5-FU in colorectal cancer patients receiving capecitabine
Capecitabine is selectively converted from 5′-DFUR to 5-fluorouracil (5-FU) in tumours by thymidine phosphorylase (TP). We investigated the addition of 5-nitrouracil (5-NU), a TP inhibitor, into blood samples ...
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Article
Open AccessCutaneous and stick rabbit illusions in individuals with autism spectrum disorder
Prediction is the process by which future events are anticipated based on past events; in contrast, postdiction is the retrospective interpretation of past events based on latter, more recent events. The predi...
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Article
Open AccessNeural correlates of tactile simultaneity judgement: a functional magnetic resonance imaging study
Simultaneity judgement (SJ) is a temporal discrimination task in which the targets span an ultimately short time range (zero or not). Psychophysical studies suggest that SJ is adequate to probe the perceptual ...
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Article
Open AccessSuvorexant (Belsomra® Tablets 10, 15, and 20 mg): Japanese Drug-Use Results Survey
We report on the results of a Japanese postmarketing drug-use survey of suvorexant (Belsomra®) tablets.
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Article
Open AccessThe p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas
Anaplastic lymphoma kinase (ALK) is an oncogenic receptor tyrosine kinase that is activated by gene amplification and mutation in neuroblastomas. ALK inhibitors can delay the progression of ALK-driven cancers,...
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Chapter and Conference Paper
Very Large-Scale Feature of Transitional and Turbulent Channel Flows: Dependence on Facilities
A recent investigation revealed that a low frequency peak in premultiplied energy spectra due to turbulent patch passes in a transitional channel flow continues in a low Reynolds number but turbulent flow. In ...
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Protocol
Studies of ATM Kinase Activity Using Engineered ATM Sensitive to ATP Analogues (ATM-AS)
Ataxia-telangiectasia mutated (ATM) protein is a member of the phosphatidylinositol 3-phosphate kinase (PI3-K)-related protein kinase (PIKK) family and is implicated in the initiation of signaling pathways fol...
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Article
Perceived empty duration between sounds of different lengths: Possible relation with repetition and rhythmic grou**
We investigated how perceived duration of empty time intervals would be modulated by the length of sounds marking those intervals. Three sounds were successively presented in Experiment 1. Each sound was short...
