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  1. Article

    Open Access

    Evaluation of a quantitative PCR-based method for chimerism analysis of Japanese donor/recipient pairs

    Chimerism analysis is a surrogate indicator of graft rejection or relapse after allogeneic hematopoietic stem cell transplantation (HSCT). Although short tandem repeat PCR (STR-PCR) is the usual method, limite...

    Keiji Minakawa, Satoshi Ono, Mao Watanabe, Yuka Sato, Saki Suzuki… in Scientific Reports (2022)

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  2. Article

    Open Access

    trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop

    trans-Fatty acids (TFAs) are unsaturated fatty acids that contain one or more carbon-carbon double bonds in trans configuration. Epidemiological evidence has linked TFA consumption with various disorders, includi...

    Yusuke Hirata, Aya Inoue, Saki Suzuki, Miki Takahashi, Ryosuke Matsui… in Scientific Reports (2020)

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  3. No Access

    Article

    Pro-caspase-3 protects cells from polymyxin B-induced cytotoxicity by preventing ROS accumulation

    Polymyxin B (PMB), a last-line antibiotic used against antibiotic-resistant superbugs, causes undesirable cytotoxic side effects. However, its mechanisms remain unknown. In this study, we unexpectedly found th...

    Takumi Yokosawa, Mayuka Yamada, Takuya Noguchi, Saki Suzuki… in The Journal of Antibiotics (2019)