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Article
Open AccessInvestigation of clinicopathological characteristics and prognosis of abdominal Desmoid tumors
Abdominal desmoid tumors (DTs) are rare soft-tissue neoplasms known for their relatively high local recurrence rate. This study aims to elucidate the clinicopathological features and investigate prognostic fac...
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Article
Stress Field Evolution of Antifriction Wear-Resistant Sealing Coatings on GH4169 Superalloy Substrate under Thermal Shock
Finger sealing has potential application prospects in aerospace engines and gas turbines. An antifriction wear-resistant sealing coating (AWSC) is used on the rotor seal track to improve the service life of a ...
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Article
Open AccessTraction power systems for electrified railways: evolution, state of the art, and future trends
Traction power systems (TPSs) play a vital role in the operation of electrified railways. The transformation of conventional railway TPSs to novel structures is not only a trend to promote the development of e...
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Article
Open AccessElasticity-controlled jamming criticality in soft composite solids
Soft composite solids are made of inclusions dispersed within soft matrices. They are ubiquitous in nature and form the basis of many biological tissues. In the field of materials science, synthetic soft compo...
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Chapter and Conference Paper
Stochastic Dynamics of a Unilateral Vibro-impact System Driven by Gaussian White Noise
Vibro-impact has the vital influence on the dynamic properties, reliability and service life of the system, which exists widely in mechanical systems. The purpose of this paper is to investigate the stochastic...
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Article
Open AccessLonidamine liposomes to enhance photodynamic and photothermal therapy of hepatocellular carcinoma by inhibiting glycolysis
Phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has great promise in the treatment of cancer. However, there are many obstacles that can restrict the therapeutic efficacy of ...
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Article
U-net Models Based on Computed Tomography Perfusion Predict Tissue Outcome in Patients with Different Reperfusion Patterns
Evaluation of cerebral perfusion is important for treatment selection in patients with acute large vessel occlusion (LVO). To assess ischemic core and tissue at risk more accurately, we developed a deep learni...
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Article
Open AccessActivation of the human insulin receptor by non-insulin-related peptides
The human insulin receptor signalling system plays a critical role in glucose homeostasis. Insulin binding brings about extensive conformational change in the receptor extracellular region that in turn effects...
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Article
Open AccessscRNA-seq of gastric tumor shows complex intercellular interaction with an alternative T cell exhaustion trajectory
The tumor microenvironment (TME) in gastric cancer (GC) has been shown to be important for tumor control but the specific characteristics for GC are not fully appreciated. We generated an atlas of 166,533 cell...
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Article
Open AccessThe aphrodisiac potential of β-cyclodextrin–curcumin via stimulating cAMP-PKA pathway in testicular Leydig cells
The water-soluble β-cyclodextrin–curcumin (CDC) is used in pharmaceutical applications and as a natural food colorant. The previous study revealed that curcumin potentially impacted the reproductive system. Th...
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Reference Work Entry In depth
Fiber-Optic Cable
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Reference Work Entry In depth
Umbilical Cable
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Reference Work Entry In depth
Cable
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Article
Open AccessAnalysis of rail potential and stray current in MVDC railway electrification system
In contrast to the conventional direct current railway electrification system (DC-RES), the medium voltage direct current (MVDC)-RES is considered promising for long-distance high-speed corridors. In the MVDC-...
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Article
Open AccessMucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies
A candidate multigenic SARS-CoV-2 vaccine based on an MVA vector expressing both viral N and S proteins (MVA-S + N) was immunogenic, and induced T-cell responses and binding antibodies to both antigens but in ...
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Article
Iodinated Contrast Agents Reduce the Efficacy of Intravenous Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Patients: a Multicenter Cohort Study
This study aimed to investigate whether the application of iodinated contrast agents before intravenous (IV) recombinant tissue plasminogen activator (rt-PA) reduces the efficacy in acute ischemic stroke (AIS)...
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Article
Open AccessA power-quality monitoring and assessment system for high-speed railways based on train-network-data center integration
In recent years, with the rapid development of high-speed railways (HSRs), power interruptions or disturbances in traction power supply systems have become increasingly dangerous. However, it is often impossib...
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Article
Indications for adjuvant chemotherapy in patients with pT1N1M0 gastric cancer: a single-center experience
Whether adjuvant chemotherapy (AC) has a survival benefit for all patients with pathological stage pT1N1M0 (Stage IB) gastric cancer (GC) remains controversial.
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Article
Open AccessModulation of BRD4 in HIV epigenetic regulation: implications for finding an HIV cure
Following reverse transcription, HIV viral DNA is integrated into host cell genomes and establishes a stable latent infection, which has posed a major obstacle for obtaining a cure for HIV. HIV proviral transc...
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Article
Point cloud segmentation for complex microsurfaces based on feature line fitting
Surfaces based on feature line constraints have higher accuracy than free-form surfaces and can capture other geometric relations of the model. The parts of complex microsurfaces are formed by arrays and cross...
