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  1. No Access

    Chapter and Conference Paper

    Dynamic of Thrombin Generation in Patients with Severe Hemophilia A

    In hemophilia A, determination of factor VIII activity is used to classify the extent of impaired hemostasis and to estimate bleeding risks of patients. In contrast, the now established assays of thrombin gene...

    Dr. F. Wenzel, H. H. Brackmann, Prof. J. Oldenburg in 37th Hemophilia Symposium (2008)

  2. No Access

    Chapter and Conference Paper

    Simultaneous Bilateral Total Knee Arthroplasty in Hemophilic Arthopathy

    This case report demonstrates that, in selected hemophilic patients, simultaneous bilateral knee replacement surgery can be performed with a good outcome without a significant increase in perioperative risk.Th...

    H. H. Eickhoff, F. W. Koch, G. Goldmann… in 36th Hemophilia Symposium Hamburg 2005 (2007)

  3. No Access

    Chapter and Conference Paper

    Alternative Therapy such as the Acupuncture of the Skull for Hemophilic Arthropathy

    T. A. Wallny, H. -H. Brackmann, G. Gunia… in 36th Hemophilia Symposium Hamburg 2005 (2007)

  4. No Access

    Chapter and Conference Paper

    Mutation Type Dependent Inhibitor Risk — a Single Center Study on 432 Patients with Severe Hemophilia A

    J. Oldenburg, J. Schröder, R. Schwaab, C. Müller-Reible… in 35th Hemophilia Symposium (2006)

  5. No Access

    Chapter and Conference Paper

    Magnetic Field Therapy in Patients with Severe Hemophilia — Motion Analysis and Quality Control

    A. Seuser, G. Schumpe, T. Wallny, H.-H. Brackmann in 35th Hemophilia Symposium (2006)

  6. No Access

    Chapter and Conference Paper

    Unusual Prolonged Course of an Immune Tolerance Therapy (ITT) in a Patient with Severe Hemophilia A and a High-Titer Inhibitor Development

    S. Meister, T. Spranger, K. Christensen, H.-H. Brackmann… in 35th Hemophilia Symposium (2006)

  7. No Access

    Chapter and Conference Paper

    Motion Analysis Epidemiology in Hemophilic Children

    A. Seuser, G. Schumpe, T. Wallny, H.-H. Brackmann in 35th Hemophilia Symposium (2006)

  8. No Access

    Chapter and Conference Paper

    Coagulation Factor XIII Mutation Profile: Update 2004

    V. Ivaskevicius, R. Seitz, H.-H. Brackmann, W. Eberl… in 35th Hemophilia Symposium (2006)

  9. No Access

    Chapter and Conference Paper

    Lack of Factor VIII Expression Represents a Novel Mechanism Leading to Hemophilia A

    O. El-Maarri, H. Singer, H.-H. Brackmann, J. Schröder, J. Graw… in 35th Hemophilia Symposium (2006)

  10. No Access

    Chapter and Conference Paper

    HLA Profile in Acquired Hemophilia

    The DR16 and DQB0502 alleles were more frequent in acquired hemophilia A than in the normal population. Although not statistically significant, the HLA profile in acquired hemophilia A gains importance because...

    Dr. J. Oldenburg, Frau Dr. A. Pavlova, J. Schröder… in 34th Hemophilia Symposium (2005)

  11. No Access

    Chapter and Conference Paper

    Sport and Physical Fitness Recommendations for Young Hemophiliacs

    Today’s generation of hemophiliac children benefits from adequate substitution and radiologically and clinically healthy joints. With self-confidence on their side, it is natural for these young people to want...

    A. Seuser, A. Kurme, T. Wallny, E. Trunz-Carlisi, S. Ochs… in 33rd Hemophilia Symposium (2004)

  12. No Access

    Chapter and Conference Paper

    Functional Analysis as a Basis for Optimizing Physiotherapy in Hemophilic Children

    A generation of hemophiliacs with no bleeding-related impairment of the locomotor system has grown up in Germany over the past two decades. This happy circumstance is the result of preventive treatment of the ...

    A. Seuser, U. Schulte-Overberg, T. Wallny, G. Schumpe… in 33rd Hemophilia Symposium (2004)

  13. No Access

    Chapter and Conference Paper

    Analysis of Factor VIII RNA from Hemophilia A Patients with no Detectable Mutation in the Coding Regions

    Here on we report on the detailed RNA analysis of the factor VIII cDNA from patients that have either putative splicing site mutations or patients with no previously detected DNA mutations by mutation screenin...

    O. El-Maarri, U. Herbiniaux, M. Watzka, J. Graw, C. Uen… in 33rd Hemophilia Symposium (2004)

  14. No Access

    Chapter and Conference Paper

    Pain Versus Clinical and Radiological Assessment in Hemophilic Arthropathies

    There seems to be a general consensus in the literature that clinical and radiographic findings correctly depict the severity of hemophilic arthropathy [1–3]. Though joint pain is known to be the symptom that enc...

    T. Wallny, L. Lahaye, H.-H. Brackmann, A. Seuser, C. N. Kraft in 33rd Hemophilia Symposium (2004)

  15. No Access

    Chapter and Conference Paper

    Rehabilitation — A Topic for Hemophiliacs?

    I’m very pleased to start this conference on’ hemophilia and sport” with my report about the importance of rehabilitation in connection with complete care of hemophiliacs. Rehabilitation measures often have a ...

    K. Vermöhlen, H.-H. Brackmann, W. Kalnins in 33rd Hemophilia Symposium (2004)

  16. No Access

    Chapter and Conference Paper

    Adenovirus-mediated regulatable Expression of human Factor IX in vitro and in vivo

    The ability to modulate transgene expression in vivo not only will mimic the expression of endogenous genes but is also important for therapeutic and safety reasons in gene therapy protocols. Regulated gene expre...

    M. A. Srour, H. Fechner, X. Wang, U. Siemetzki, T. Albert… in 32nd Hemophilia Symposium (2003)

  17. No Access

    Chapter and Conference Paper

    A Life-threatening Cardiomyopathy following Port-a-Cath Infection under Immune Tolerance Therapy

    For elimination of inhibitors against factor VIII immune tolerance therapy (Bonnor Malmö-protocol) is Mainly used. It requires intravenous injections twice daily up to several Months — while in early infancy a...

    G. Wiegand, R. Rauch, W. Effenberger, H.-H. Brackmann… in 32nd Hemophilia Symposium (2003)

  18. No Access

    Chapter and Conference Paper

    Rhenium-186 Hydroxyethylidenediphosphonate (186Re HEDP) — A novel Treatment for hemophilic Arthropathies?

    Patients diagnosed with hemophilia before the era of home infusion frequently suffer from severe hemarthropathies. Treatment usually relies on physiotherapy for Muscular atrophy and to improve, or at least Mai...

    T. A. Wallny, L. Hess, H.-H. Brackmann, A. Seuser, H. Palmedo… in 32nd Hemophilia Symposium (2003)

  19. No Access

    Chapter and Conference Paper

    Transmission of Parvovirus B19 by Heat-treated Coagulation Factor Concentrates

    Transmission of enveloped viruses by blood products prepared from pooled plasma has fortunately become an extremely rare event due to the efficacy of the applied virus inactivation procedures. The inactivation...

    J. Blümel, I. Schmidt, W. Effenberger, H. Seitz, H. Willkommen… in 32nd Hemophilia Symposium (2003)

  20. No Access

    Chapter and Conference Paper

    11 novel Mutations in the Factor VIII encoding Gene lead to severe or moderate Hemophilia A

    In Germany, approximately 5800 patients are suffering from hemophilia A. In a systematic large-scale analysis we will identify the genotype of all severe cases (approximately 3000 patients). A first screening ...

    C. Uen, N. Klopp, J. Oldenburg, H.-H. Brackmann, W. Schramm… in 32nd Hemophilia Symposium (2003)

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