113 Result(s)
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Guowei **ao
Life Sciences
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Article
Effects of Testosterone in Mediating the Relationship Between Daytime Nap** and Osteoporosis in European Populations: A Mendelian Randomization Study
We aimed to explore the causal effect of daytime nap** on the risk of osteoporosis and the mediation role of testosterone in explaining this relationship. Summary data for Mendelian randomization (MR) analys...
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Counting, locating, and sizing of shrimp larvae based on density map regression
The count, location, and size of shrimp larvae are important observations for their intensive breeding, which could evaluate the culture density, growth, and yield. Recent works on the counting of dense aquati...
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Article
Peanut LEAFY COTYLEDON1-type genes participate in regulating the embryo development and the accumulation of storage lipids
Two peanut LEC1-type genes exhibit partial functional redundancy. AhNFYB10 could complement almost all the defective phenotypes of lec1-2 in terms of embryonic morphology, while AhNF-YB1 could partially affect th...
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Recent advances of sesquiterpenoid dimers from Compositae: distribution, chemistry and biological activities
Composite family contains a wide variety of plants and many of them possess high medicinal value. Various constituents have been isolated from members of Composite family. Sesquiterpenoids prove to be the char...
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Open AccessTFEB and TFE3 cooperate in regulating inorganic arsenic-induced autophagy-lysosome impairment and immuno-dysfunction in primary dendritic cells
Arsenic (As) is a prevalent and hazardous environmental toxicant associated with cancer and various health problems, which has been shown suppressive effects on dendritic cells (DCs). Autophagy is essential fo...
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KLF4 facilitates chromatin accessibility remodeling in porcine early embryos
Chromatin accessibility remodeling driven by pioneer factors is critical for the development of early embryos. Current studies have illustrated several pioneer factors as being important for agricultural anima...
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Characterization, Expression, and Functional Analysis of the Northern Snakehead (Channa argus) Hepcidin
Hepcidin, an antimicrobial peptide (AMP), is a well-conserved molecule present in various species such as fish, amphibians, birds, reptiles, and mammals. It exhibits broad-spectrum antimicrobial activity and h...
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Open AccessGenome wide analysis revealed conserved domains involved in the effector discrimination of bacterial type VI secretion system
Type VI secretion systems (T6SSs) deliver effectors into target cells. Besides structural and effector proteins, many other proteins, such as adaptors, co-effectors and accessory proteins, are involved in this...
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Open AccessA novel complementary pathway of cordycepin biosynthesis in Cordyceps militaris
We determined whether there exists a complementary pathway of cordycepin biosynthesis in wild-type Cordyceps militaris, high-cordycepin-producing strain C. militaris GYS60, and low-cordycepin-producing strain C. ...
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Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972
There are six new phthalide derivatives Verbalide A ~ F (1–6) together with another known derivative (7) isolated from the endophytic fungus Preussia sp. CPCC 400972. Their structures were established by comprehe...
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Impacts of acute cold-stress in Pacific white shrimp Litopenaeus vannamei: investigating the tissue-specific stress resistance response
Temperature is one of the key environmental factors in Litopenaeus vannamei (Boone, 1931) culture, affecting the growth and survival of shrimp. Our previous study found that stress resistance related pathways (en...
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The acetyltransferase BmCBP changes the acetylation modification of BmSP3 and affects its protein expression in silkworm, Bombyx mori
Protein acetylation is an important post-translational modification (PTM) that widely exists in organisms. As a reversible PTM, acetylation modification can regulate the function of proteins with high efficien...
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Open AccessBCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma
There is an urgent need for novel diagnostic and therapeutic strategies for patients with Glioblastoma multiforme (GBM). Previous studies have shown that BCL2 like 13 (BCL2L13) is a member of the BCL2 family r...
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Open AccessGenome-wide chromatin accessibility landscape and dynamics of transcription factor networks during ovule and fiber development in cotton
The development of cotton fiber is regulated by the orchestrated binding of regulatory proteins to cis-regulatory elements associated with developmental genes. The cis–trans regulatory dynamics occurred throughou...
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Genome Analysis and Safety Assessment of Achromobacter marplatensis Strain YKS2 Strain Isolated from the Rumen of Yaks in China
Achromobacter marplatensis strain YKS2 isolated from the yak rumen has the feature of producing cellulose. This study aims to analyze the genome and safety of strain YKS2 in vivo, considering its future research ...
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Ecological Stoichiometry of Soil Carbon, Nitrogen and Phosphorus in Reclaimed Farmland in Coal Mining Subsidence Area
The soil carbon, nitrogen and phosphorus content and stoichiometric characteristics of reclaimed farmland were explored, providing basic data for reclaimed farmland management. Samples of reclaimed farmland so...
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Open AccessMultiomics strategies for decoding seed dormancy breakdown in Paris polyphylla
The disruption of seed dormancy is a complicated process and is controlled by various factors. Among these factors, membrane lipids and plant hormones are two of the most important ones. Paris polyphylla is an im...
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Four new chromone derivatives from the Arctic fungus Phoma muscivora CPCC 401424 and their antiviral activities
The crude extract of the Arctic fungus Phoma muscivora CPCC 401424 displayed anti-influenza A virus activities which led us to investigated their secondary metabolites. Four new chromone derivatives, phomarcticon...
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Open AccessEffect of cold stratification on the temperature range for germination of Pinus koraiensis
Germination at low spring temperatures may offer a competitive advantage for the growth and survival of plant species inhabiting temperate forest ecosystems. Pinus koraiensis is a dominant species in temperate fo...
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Open AccessThe CDK inhibitor AT7519 inhibits human glioblastoma cell growth by inducing apoptosis, pyroptosis and cell cycle arrest
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor with a poor median survival of less than 15 months. However, clinical strategies and effective therapies are limited. Here, we found that th...
