138 Result(s)

Article

Potential decoupling of CO₂ and Hg uptake process by global vegetation in the 21st century

Mercury (Hg), a potent neurotoxin posing risks to human health, is cycled through vegetation uptake, which is susceptible to climate change impacts. However, the extent and pattern of these impacts are largely...

Tengfei Yuan, Shaojian Huang, Peng Zhang, Zhengcheng Song, Jun Ge… in Nature Communications (2024)

Article

Blood lipid levels mediating the effects of sex hormone-binding globulin on coronary heart disease: Mendelian randomization and mediation analysis

Observational studies indicate that serum sex hormone-binding globulin (SHBG) levels are inversely correlated with blood lipid levels and coronary heart disease (CHD) risk. Given that dyslipidemia is an establ...

Juntao Yang, Jiedong Zhou, Hanxuan Liu, **** Hao, Songqing Hu… in Scientific Reports (2024)

Article

U3 snoRNA inter-regulates with DDX21 in the perichromosomal region to control mitosis

U3 snoRNA is essential for ribosome biogenesis during interphase. Upon mitotic onset, the nucleolus disassembles and U3 snoRNA relocates to the perichromosomal region (PR) to be considered as a chromosome pass...

Yang Jiang, Shiqi Sun, **aofeng Liu, Kunqi Su, Chunfeng Zhang… in Cell Death & Disease (2024)

Article

Retraction Note: IL-1RA inhibits esophageal carcinogenesis and lymphangiogenesis via downregulating VEGF-C and MMP9

Zhimin Shen, Peipei Zhang, Weiguang Zhang, Fei Luo… in Functional & Integrative Genomics (2024)

Article

Comparative efficacy of prophylactic protocols in reducing perioperative nausea and vomiting during video-assisted thoracoscopic radical resection of lung cancer

Lung cancer, a global mortality leader, often necessitates Video-Assisted Thoracoscopic (VATS) surgery. However, post-operative nausea and vomiting (PONV) is common, highlighting a need for effective managemen...

Weiguang Zhang, Zhimin Shen, Junfei Jiang, Shu**g Zhu, Peipei Zhang… in Scientific Reports (2024)

Article

Genome‑wide identification and expression analysis of the UBC gene family in wheat (Triticum aestivum L.)

Ubiquitination is an important regulatory step of selective protein degradation in the plant UPS (ubiquitin–proteasome system), which is involved in various biological processes in eukaryotes. Ubiquitin-conjug...

Weidong Gao, Long Zhang, Yanyan Zhang, Peipei Zhang, Fahimeh Shahinnia… in BMC Plant Biology (2024)

Article

Plasma-Free Blood as a Potential Alternative to Whole Blood for Transcriptomic Analysis

RNA sequencing (RNAseq) technology has become increasingly important in precision medicine and clinical diagnostics, and emerged as a powerful tool for identifying protein-coding genes, performing differential...

Qingwang Chen, **aorou Guo, Haiyan Wang, Shanyue Sun, He Jiang, Peipei Zhang… in Phenomics (2024)

Article

Quartet metabolite reference materials for inter-laboratory proficiency test and data integration of metabolomics profiling

Various laboratory-developed metabolomic methods lead to big challenges in inter-laboratory comparability and effective integration of diverse datasets.

Naixin Zhang, Qiaochu Chen, Peipei Zhang, Kejun Zhou, Yaqing Liu… in Genome Biology (2024)

Article

Genome-wide identification and analysis of the GGCT gene family in wheat

γ-glutamylcyclotransferase (GGCT), an enzyme to maintain glutathione homeostasis, plays a vital role in the response to plant growth and development as well as the adaptation to various stresses. Although the GGC...

Long Zhang, Wanting Sun, Weidong Gao, Yanyan Zhang, Peipei Zhang, Yuan Liu… in BMC Genomics (2024)

Article

IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G

Triple-negative breast cancers (TNBC) are highly aggressive malignancies with poor prognosis. As an essential enzyme in the tryptophan–kynurenine metabolic pathway, indoleamine 2,3 dioxygenase-1 (IDO-1) has be...

Rui **g, Shukun Bai, Peipei Zhang, Hao Ren, Lintao Jia, Weimiao Li… in Breast Cancer (2024)

Article

Genome-wide analysis of long noncoding RNAs in response to salt stress in Nicotiana tabacum

Long noncoding RNAs (lncRNAs) have been shown to play important roles in the response of plants to various abiotic stresses, including drought, heat and salt stress. However, the identification and characteriz...

Zefeng Li, Huina Zhou, Guoyun Xu, Peipei Zhang, Niu Zhai… in BMC Plant Biology (2023)

Article

Correction: The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast

Wenwen Yu, Yi Zheng, Hongyan Li… in Journal of Orthopaedic Surgery and Research (2023)

Article

Systematic review and network meta-analysis of robot-assisted gait training on lower limb function in patients with cerebral palsy

This study aimed to evaluate the effectiveness of robot-assisted gait training (RAGT) in treating lower extremity function in patients with cerebral palsy (CP) and compare the efficacy differences between diff...

Yueying Wang, Peipei Zhang, Chao Li in Neurological Sciences (2023)

Article

Acteoside protects podocyte against apoptosis through regulating AKT/GSK-3β signaling pathway in db/db mice

Podocyte apoptosis is one of the important pathological mechanisms of diabetic kidney disease (DKD). Acteoside (Act), a major active component of Rehmannia glutinosa leaves total glycoside, has a strong renopr...

**aoya Li, Zhilong Liu, Zhixiu He, **aocheng Wang, Rongshan Li… in BMC Endocrine Disorders (2023)

Article

Author Correction: Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling

Ying Yu, Wanwan Hou, Yaqing Liu, Haiyan Wang, Lianhua Dong… in Nature Biotechnology (2023)

Article

LncRNA SNHG1: role in tumorigenesis of multiple human cancers

Small nucleolar RNA host gene 1 (SNHG1) is an important member of the SNHG family. This family is composed of a group of host genes that can be processed into small nucleolar RNAs and play important biological...

Huang Zeng, Shouang Zhou, Weiqiang Cai, Mingqiang Kang… in Cancer Cell International (2023)

Article

Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling

Certified RNA reference materials are indispensable for assessing the reliability of RNA sequencing to detect intrinsically small biological differences in clinical settings, such as molecular subty** of dis...

Ying Yu, Wanwan Hou, Yaqing Liu, Haiyan Wang, Lianhua Dong… in Nature Biotechnology (2023)

Article

Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials

Characterization and integration of the genome, epigenome, transcriptome, proteome and metabolome of different datasets is difficult owing to a lack of ground truth. Here we develop and characterize suites of ...

Yuanting Zheng, Yaqing Liu, **gcheng Yang, Lianhua Dong, Rui Zhang… in Nature Biotechnology (2023)

Article

Human umbilical cord mesenchymal stromal cell small extracellular vesicle transfer of microRNA-223-3p to lung epithelial cells attenuates inflammation in acute lung injury in mice

Acute lung injury (ALI), manifested as strong pulmonary inflammation and alveolar epithelial damage, is a life-threatening disease with high morbidity and mortality. Small extracellular vesicles (sEVs), secret...

Jie Chen, Shiyang Ma, Baihua Luo, Haojie Hao, Yanqin Li… in Journal of Nanobiotechnology (2023)

Article

KRT18 regulates trophoblast cell migration and invasion which are essential for embryo implantation

Female infertility is a worldwide concern that impacts the quality of life and well-being of affected couples. Failure of embryo implantation is a major cause of early pregnancy loss and is precisely regulated...

**aoling Liang, **aoxiao Qiu, Yana Ma, Wenzhi Xu… in Reproductive Biology and Endocrinology (2023)