3 Result(s)

Article

The classical pathway triggers pathogenic complement activation in membranous nephropathy

Membranous nephropathy (MN) is an antibody-mediated autoimmune disease characterized by glomerular immune complexes containing complement components. However, both the initiation pathways and the pathogenic si...

Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger… in Nature Communications (2023)

Article

Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

Little is known about the mechanistic significance of the ubiquitin proteasome system (UPS) in a kidney autoimmune environment. In membranous nephropathy (MN), autoantibodies target podocytes of the glomerular...

Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert… in Nature Communications (2023)

Article

Publisher Correction: Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert… in Nature Communications (2023)