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Article
Open AccessHobit expression by a subset of human liver-resident CD56bright Natural Killer cells
Immune responses show a high degree of tissue specificity shaped by factors influencing tissue egress and retention of immune cells. The transcription factor Hobit was recently shown to regulate tissue-residen...
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Article
Open AccessPeptide-specific engagement of the activating NK cell receptor KIR2DS1
The activating NK cell receptor KIR2DS1 has been shown to be involved in many disorders including autoimmune diseases, malignancies and pregnancy outcomes. However, the precise ligands and functions of this re...
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Article
Open AccessChanges in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture
Human immunodeficiency virus type 1 (HIV-1) has a biased nucleotide composition different from human genes. This raises the question of how evolution has chosen the nucleotide sequence of HIV-1 that is observe...
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Chapter
Quasispecies Dynamics of RNA Viruses
RNA viruses, such as human immunodeficiency virus, hepatitis C virus, influenza virus, and poliovirus replicate with very high mutation rates and exhibit very high genetic diversity. The extremely high genetic...
