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Article
Open AccessTissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
Innate lymphoid cells (ILC), including natural killer (NK) cells, are implicated in host-defense and tissue-growth. However, the composition and kinetics of NK cells in the intestine during the first year of l...
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Article
Open AccessHobit expression by a subset of human liver-resident CD56bright Natural Killer cells
Immune responses show a high degree of tissue specificity shaped by factors influencing tissue egress and retention of immune cells. The transcription factor Hobit was recently shown to regulate tissue-residen...
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Article
Open AccessPeptide-specific engagement of the activating NK cell receptor KIR2DS1
The activating NK cell receptor KIR2DS1 has been shown to be involved in many disorders including autoimmune diseases, malignancies and pregnancy outcomes. However, the precise ligands and functions of this re...
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Immunopathogenesis of Hepatitis D
Infection with the hepatitis D virus (HDV) causes hepatitis delta, which is considered to be the most severe form of viral hepatitis. HDV is a defective virus, using the hepatitis B virus (HBV) surface antigen...