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Article
Open AccessAvailability and use of Standards in vaccine development
Reference materials are critical in assay development for calibrating and assessing their suitability. The devasting nature of the COVID-19 pandemic and subsequent proliferation of vaccine platforms and techno...
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Article
Open AccessPassive immunisation of convalescent human anti-Zika plasma protects against challenge with New World Zika virus in cynomolgus macaques
Zika virus (ZIKV) causes neurological complications in susceptible individuals, highlighted in the recent South American epidemic. Natural ZIKV infection elicits host responses capable of preventing subsequent...
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Article
Open AccessHarmonization of Zika neutralization assays by using the WHO International Standard for anti-Zika virus antibody
During outbreaks of emerging viruses, such as the Zika outbreak in 2015–2016, speed and accuracy in detection of infection are critical factors to control the spread of the disease; often serological and diagn...
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Article
Open AccessIdentifying features of the lentiviral genome crucial for the establishment of latency
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Article
Open AccessAnti-retroviral innate immune responses in multiple lymphoid tissues elicited by protective live attenuated SIV vaccination
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Article
Open AccessDifferential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent species
The risk of zoonotic infection by porcine endogenous retroviruses (PERV) has been highlighted in the context of pig-to-human xenotransplantation. The use of receptors for cell entry often determines the host r...