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Article
Open AccessReplication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against homologous and heterologous wild-type challenge in macaques
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Article
Open AccessOccult replication of a conditionally-live attenuated SIV profoundly upregulates T effector memory cell frequency
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Article
Open AccessAnti-retroviral innate immune responses in multiple lymphoid tissues elicited by protective live attenuated SIV vaccination
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Protocol
Detection, Quantification, and Characterisation of HIV/SIV
Selected techniques for the detection, quantification, and characterisation of HIV1, HIV2, and SIV, as applied to diagnostic and research purposes, are described. Representative nucleic acid testing protocols ...
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Article
Open AccessReplication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against SIVmac239 wild-type challenge in a rhesus macaque model
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Article
Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques
Prevention of sexually transmitted HIV infection was investigated in macaques by immunization with a recombinant SIV (simian immunodeficiency virus) envelope gp120 and core p27 vaccine. In two independent seri...
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Article
Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques
In order to develop a successful subunit vaccine against infection with the human immunodeficiency virus (HIV), protective immune effector functions must be identified. Until now, there has been only indirect ...