-
Article
Open AccessDoes preoperative multidisciplinary team assessment of high-risk patients improve the safety and outcomes of patients undergoing surgery?
International guidelines recommend preoperative multidisciplinary team (MDT) assessment for high-risk surgical patients. Preoperative MDT meetings can help to improve surgical care, but there is little evidenc...
-
Article
Selective Decontamination with Oral Antibiotics in Colorectal Surgery: 90-day Reintervention Rates and Long-term Oncological Follow-up
Oral antibiotics (OAB) in colorectal surgery have been shown to reduce surgical site infections (SSIs) and possibly anastomotic leakage. However, evidence on long-term follow-up, reintervention rates and 5-yea...
-
Article
Open AccessPerspectives of patients with colorectal cancer liver metastases on e-consultation in transmural care: a qualitative study
Comprehensive cancer networks have been established to deliver high-quality care for patients with cancer. Logistic challenges are faced, when patients need to be referred for specialized treatments. Despite s...
-
Article
Open AccessCorrection: Impact of shifting from laparoscopic to robotic surgery during 600 minimally invasive pancreatic and liver resections
-
Article
Open AccessImpact of shifting from laparoscopic to robotic surgery during 600 minimally invasive pancreatic and liver resections
Many centers worldwide are shifting from laparoscopic to robotic minimally invasive hepato-pancreato-biliary resections (MIS-HPB) but large single center series assessing this process are lacking. We hypothesi...
-
Article
Open AccessCorrection: Stereotactic ablative radiotherapy or best supportive care in patients with localized pancreatic cancer not receiving chemotherapy and surgery (PANCOSAR): a nationwide multicenter randomized controlled trial according to a TwiCs design
-
Article
Open AccessStereotactic ablative radiotherapy or best supportive care in patients with localized pancreatic cancer not receiving chemotherapy and surgery (PANCOSAR): a nationwide multicenter randomized controlled trial according to a TwiCs design
Significant comorbidities, advanced age, and a poor performance status prevent surgery and systemic treatment for many patients with localized (non-metastatic) pancreatic ductal adenocarcinoma (PDAC). These pa...
-
Article
Open AccessDragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy
The DRAGON 1 trial aims to assess training, implementation, safety and feasibility of combined portal- and hepatic-vein embolization (PVE/HVE) to accelerate future liver remnant (FLR) hypertrophy in patients w...
-
Article
Clinical relevant pancreatic fistula after pancreatoduodenectomy: when negative amylase levels tell the truth
Drain Amylase level are routinely determined to diagnose pancreatic fistula after Pancreatocoduodenectomy. Consensus is lacking regarding the cut-off value of amylase to diagnosis clinically relevant postopera...
-
Article
Open AccessFocal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease, with minimal therapeutic options. Aberrant tyrosine kinase activity influences tumor growth and is regulated by phosphorylation. We investigate...
-
Article
Open AccessConservative treatment versus elective repair of umbilical hernia in patients with liver cirrhosis and ascites: results of a randomized controlled trial (CRUCIAL trial)
To establish optimal management of patients with an umbilical hernia complicated by liver cirrhosis and ascites.
-
Article
Open AccessDetection of colorectal cancer in urine using DNA methylation analysis
Colorectal cancer (CRC) is the second leading cause for cancer-related death globally. Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the feasibility of CRC detection b...
-
Article
Open AccessCo-expression analysis of pancreatic cancer proteome reveals biology and prognostic biomarkers
Despite extensive biological and clinical studies, including comprehensive genomic and transcriptomic profiling efforts, pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease, with a poor survi...
-
Article
Open AccessEmergency repair of inguinal hernia in the premature infant is associated with high direct medical costs
Inguinal hernia repair is frequently performed in premature infants. Evidence on optimal management and timing of repair, as well as related medical costs is still lacking. The objective of this study was to d...
-
Article
Open AccessClinical picture: multiple sites of ectopic pancreatic tissue
A case is presented with multiple sites of ectopic pancreatic tissue in the gastro-intestinal tract. The sites were found in the stomach and duodenum, one site of ectopic pancreatic tissue presented with necro...
-
Article
Incisional Hernia: Plastic Aspects, Component Separation, Technical Details & Pediatrics
-
Article
Ablation of colorectal liver metastases by irreversible electroporation: results of the COLDFIRE-I ablate-and-resect study
Irreversible electroporation (IRE) is a new ablation technique that relies on high-voltage electrical pulses. This clinical study evaluates the pathological response of colorectal liver metastases (CRLM) treat...
-
Article
Serum Level of Ca 19-9 Increases Ability of IgG4 Test to Distinguish Patients with Autoimmune Pancreatitis from Those with Pancreatic Carcinoma
Autoimmune pancreatitis (AIP) is often difficult to distinguish from pancreatic carcinoma or other pancreatobiliary diseases. High serum levels of carbohydrate antigen 19-9 (Ca 19-9) are indicative of malignan...
-
Article
Comment on Research Article Entitled “Variability of Subspecialty-Specific Anesthesia-Controlled Times at Two Academic Institutions” as published in J Med Syst 2014; 38 (11)
-
Article
Management of biliary complications following damage control surgery for liver trauma
The liver is the most frequently injured solid intra-abdominal organ. The major cause of early death following severe liver trauma is exsanguination. Although perihepatic packing improves survival in severe li...
