28 Result(s)

Article

Recurrent disease detection after resection of pancreatic ductal adenocarcinoma using a recurrence-focused surveillance strategy (RADAR-PANC): protocol of an international randomized controlled trial according to the Trials within Cohorts design

Disease recurrence remains one of the biggest concerns in patients after resection of pancreatic ductal adenocarcinoma (PDAC). Despite (neo)adjuvant systemic therapy, most patients experience local and/or dist...

L. A. Daamen, I. W. J. M. van Goor, V. P. Groot, P. C. M. Andel, L. A. A. Brosens… in Trials (2024)

Article

Perioperative or adjuvant mFOLFIRINOX for resectable pancreatic cancer (PREOPANC-3): study protocol for a multicenter randomized controlled trial

Surgical resection followed by adjuvant mFOLFIRINOX (5-fluorouracil with leucovorin, irinotecan, and oxaliplatin) is currently the standard of care for patients with resectable pancreatic cancer. The main conc...

J. L. van Dam, E. M. M. Verkolf, E. N. Dekker, B. A. Bonsing, S. O. Bratlie… in BMC Cancer (2023)

Article

Correction: Impact of shifting from laparoscopic to robotic surgery during 600 minimally invasive pancreatic and liver resections

Anouk. M. L. H. Emmen, B. Görgec, M. J. W. Zwart, F. Daams… in Surgical Endoscopy (2023)

Article

Impact of shifting from laparoscopic to robotic surgery during 600 minimally invasive pancreatic and liver resections

Many centers worldwide are shifting from laparoscopic to robotic minimally invasive hepato-pancreato-biliary resections (MIS-HPB) but large single center series assessing this process are lacking. We hypothesi...

Anouk. M. L. H. Emmen, B. Görgec, M. J. W. Zwart, F. Daams… in Surgical Endoscopy (2023)

Article

Correction: Prophylactic abdominal drainage or no drainage after distal pancreatectomy (PANDORINA): a study protocol of a binational multicenter randomized controlled trial

F. L. Vissers, A. Balduzzi, E. A. van Bodegraven, J. van Hilst, S. Festen… in Trials (2023)

Article

Correction: A nationwide randomized controlled trial on additional treatment for isolated local pancreatic cancer recurrence using stereotactic body radiation therapy (ARCADE)

I. W. J. M. van Goor, L. A. Daamen, M. G. Besselink, A. M. E. Bruynzeel… in Trials (2023)

Article

Correction: Stereotactic ablative radiotherapy or best supportive care in patients with localized pancreatic cancer not receiving chemotherapy and surgery (PANCOSAR): a nationwide multicenter randomized controlled trial according to a TwiCs design

D. Doppenberg, M. G. Besselink, C. H. J. van Eijck, M. P. W. Intven… in BMC Cancer (2023)

Article

Stereotactic ablative radiotherapy or best supportive care in patients with localized pancreatic cancer not receiving chemotherapy and surgery (PANCOSAR): a nationwide multicenter randomized controlled trial according to a TwiCs design

Significant comorbidities, advanced age, and a poor performance status prevent surgery and systemic treatment for many patients with localized (non-metastatic) pancreatic ductal adenocarcinoma (PDAC). These pa...

D. Doppenberg, M. G. Besselink, C. H. J. van Eijck, M. P. W. Intven… in BMC Cancer (2022)

Article

A nationwide randomized controlled trial on additional treatment for isolated local pancreatic cancer recurrence using stereotactic body radiation therapy (ARCADE)

Disease recurrence is the main cause of mortality after resection of pancreatic ductal adenocarcinoma (PDAC). In 20–30% of resected patients, isolated local PDAC recurrence occurs. Retrospective studies have s...

I. W. J. M. van Goor, L. A. Daamen, M. G. Besselink, A. M. E. Bruynzeel… in Trials (2022)

Article

Painful lower limb nodules as first symptom of resectable pancreatic acinar cell cancer: a case report

Pancreatic panniculitis is characterized by subcutaneous fat necrosis and is a rare presentation of an underlying pancreatic disease, appearing in approximately 2–3% of all patients with a pancreatic disease. ...

S. M. Haenen, J. A. M. G. Tol, S. C. J. van Steen… in Journal of Medical Case Reports (2022)

Article

Prophylactic abdominal drainage or no drainage after distal pancreatectomy (PANDORINA): a study protocol of a binational multicenter randomized controlled trial

Prophylactic abdominal drainage is current standard practice after distal pancreatectomy (DP), with the aim to divert pancreatic fluid in case of a postoperative pancreatic fistula (POPF) aimed to prevent furt...

F. L. Vissers, A. Balduzzi, E. A. van Bodegraven, J. van Hilst, S. Festen… in Trials (2022)

Article

Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): study protocol for an international multicentre prospective diagnostic accuracy study

Abdominal computed tomography (CT) is the standard imaging method for patients with suspected colorectal liver metastases (CRLM) in the diagnostic workup for surgery or thermal ablation. Diffusion-weighted and...

B. Görgec, I. Hansen, G. Kemmerich, T. Syversveen, M. Abu Hilal… in BMC Cancer (2021)

Article

Risk factors and outcomes of conversion in minimally invasive distal pancreatectomy: a systematic review

The reported conversion rates for minimally invasive distal pancreatectomy (MIDP) range widely from 2 to 38%. The identification of risk factors for conversion may help surgeons during preoperative planning an...

A. Balduzzi, N. van der Heijde, A. Alseidi, S. Dokmak… in Langenbeck's Archives of Surgery (2021)

Article

Radiofrequency ablation and chemotherapy versus chemotherapy alone for locally advanced pancreatic cancer (PELICAN): study protocol for a randomized controlled trial

Approximately 80% of patients with locally advanced pancreatic cancer (LAPC) are treated with chemotherapy, of whom approximately 10% undergo a resection. Cohort studies investigating local tumor ablation with...

M. S. Walma, S. J. Rombouts, L. J. H. Brada, I. H. Borel Rinkes, K. Bosscha… in Trials (2021)

Article

Total neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy and adjuvant gemcitabine for resectable and borderline resectable pancreatic cancer (PREOPANC-2 trial): study protocol for a nationwide multicenter randomized controlled trial

Neoadjuvant therapy has several potential advantages over upfront surgery in patients with localized pancreatic cancer; more patients receive systemic treatment, fewer patients undergo futile surgery, and R0 r...

Q. P. Janssen, J. L. van Dam, B. A. Bonsing, H. Bos, K. P. Bosscha… in BMC Cancer (2021)

Article

Molecular targets for diagnostic and intraoperative imaging of pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX treatment

Neoadjuvant systemic treatment is increasingly being integrated in the standard treatment of pancreatic ductal adenocarcinoma (PDAC) patients to improve oncological outcomes. Current available imaging techniqu...

F. A. Vuijk, L. D. A. N. de Muynck, L. C. Franken, O. R. Busch… in Scientific Reports (2020)

Article

Impact of nationwide enhanced implementation of best practices in pancreatic cancer care (PACAP-1): a multicenter stepped-wedge cluster randomized controlled trial

Pancreatic cancer has a very poor prognosis. Best practices for the use of chemotherapy, enzyme replacement therapy, and biliary drainage have been identified but their implementation in daily clinical practic...

T. M. Mackay, F. J. Smits, A. E. J. Latenstein, A. Bogte, B. A. Bonsing, H. Bos… in Trials (2020)