9 Result(s)
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Francisco X Real
Life Sciences
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Article
Open AccessVitamin D opposes multilineage cell differentiation induced by Notch inhibition and BMP4 pathway activation in human colon organoids
Understanding the mechanisms involved in colonic epithelial differentiation is key to unraveling the alterations causing inflammatory conditions and cancer. Organoid cultures provide an unique tool to address ...
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Article
Open AccessErratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies
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Article
Open AccessErratum to: The UBC-40 Urothelial Bladder Cancer Cell Line Index: a genomic resource for functional studies
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Article
Open AccessThe UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies
Urothelial bladder cancer is a highly heterogeneous disease. Cancer cell lines are useful tools for its study. This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lin...
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Article
The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression
Aberrant activation of WNT signalling and loss of BMP signals represent the two main alterations leading to the initiation of colorectal cancer (CRC). Here we screen for genes required for maintaining the tumo...
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Article
Open AccessGenome-wide CNV analysis replicates the association between GSTM1 deletion and bladder cancer: a support for using continuous measurement from SNP-array data
Structural variations such as copy number variants (CNV) influence the expression of different phenotypic traits. Algorithms to identify CNVs through SNP-array platforms are available. The ability to evaluate ...
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Article
A novel functional variant in 8q24 is associated with regulation of prostate stem cell antigen (PSCA) gene expression and bladder cancer risk
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Article
A novel functional variant in 8q24 is associated with regulation of prostate stem cell antigen (PSCA) gene expression and bladder cancer risk
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Protocol
Polyclonal and Monoclonal Techniques
In the past twenty years, much progress in the study of mucins has resulted from the development of antibodies recognizing carbohydrate and peptide epitopes. Although antibodies are extremely useful reagents i...
