-
Article
Open AccessThe antagonistic effect of FTO on METTL14 promotes AKT3 m6A demethylation and the progression of esophageal cancer
As the most abundant modification in eukaryotic messenger RNAs (mRNAs), N6-methyladenosine (m6A) plays vital roles in many biological processes.
-
Article
Work volition, major satisfaction and major–job congruence: a three-wave investigation among Chinese pre-service preschool teachers
Based on prospective data from 291 pre-service preschool teachers in Northwest China, this study attempted to clarify the relationship between work volition and major–job congruence and the mediating effect of...
-
Article
Open AccessMicroRNA-193a-5p Rescues Ischemic Cerebral Injury by Restoring N2-Like Neutrophil Subsets
Circulating neutrophils are activated shortly after stroke and in turn affect the fate of ischemic brain tissue, and microRNAs (miRNA) participate in regulating neuroinflammation. We probed the role of neutrop...
-
Article
Novel S2O82−/Fe-ZrO2 solid superacid catalyst combined with O2-Ac2O for highly efficient catalytic nitration of 1-nitronaphthalene with NO2 to 1,5-dinitronaphthalene
A mild, efficient, and green approach for highly selective synthesis of 1,5-dinitronaphthalene (1,5-DNN) has been devolved from catalytic nitration of 1-nitronaphthalene (1-NN) with NO2 combined with O2-Ac2O over...
-
Article
Open AccessGut microbiome signatures of extreme environment adaption in Tibetan pig
Tibetan pigs (TPs) can adapt to the extreme environments in the Tibetan plateau implicated by their self-genome signals, but little is known about roles of the gut microbiota in the host adaption. Here, we rec...
-
Article
Functional differentiation of the ovine preadipocytes —insights from gene expression profiling
The preadipocytes differentiation is a vital process of lipogenesis; exploring the molecular mechanisms of lipogenesis contributes to improve the meat quality and final commercial income. Lipogenesis has been ...
-
Article
Open AccessColonization of Fusobacterium nucleatum is an independent predictor of poor prognosis in gastric cancer patients with venous thromboembolism: a retrospective cohort study
Fusobacterium nucleatum (F. nucleatum) often colonizes cancerous gastric tissues and is characterized by the promotion of platelet aggregation and the development of visceral thrombosis. Venous thromboembolism (V...
-
Article
Interferon-γ enhances the immunosuppressive ability of canine bone marrow-derived mesenchymal stem cells by activating the TLR3-dependent IDO/kynurenine pathway
The immunomodulatory function of mesenchymal stem cells (MSCs) has been considered to be vital for MSC-based therapies. Many works have been devoted to excavate effective strategies for enhancing the immunomod...
-
Article
Ultrasound-assisted co-precipitation synthesis of mesoporous Co3O4−CeO2 composite oxides for highly selective catalytic oxidation of cyclohexane
The one-step highly selective oxidation of cyclohexane into cyclohexanone and cyclohexanol as the essential intermediates of nylon-6 and nylon-66 is considerably challenging. Therefore, an efficient and low-co...
-
Article
Open AccessFTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells
N6-methyladenosine (m6A) is the most prevalent and internal modification that occurs in the messenger RNAs of eukaryotes. However, knowledge of the impact of these modifications on gene expression regulation rema...
-
Article
Open AccessEngineered chimeric insecticidal crystalline protein improves resistance to lepidopteran insects in rice (Oryza sativa L.) and maize (Zea mays L.)
The insecticidal crystalline proteins (Crys) are a family of insect endotoxin functioning in crop protection. As insects keep evolving into tolerance to the existing Crys, it is necessary to discover new Cry p...
-
Article
Solvent-free catalytic oxidation of toluene over heterogeneous CeMnOx composite oxides
An inexpensive and controllable CeMnOx composite oxides catalyst for the liquid-phase catalytic oxidation of toluene was conveniently prepared by ultrasound-assisted co-precipitation method. The physical–chemical...
-
Article
Open AccessLAMTOR5-AS1 regulates chemotherapy-induced oxidative stress by controlling the expression level and transcriptional activity of NRF2 in osteosarcoma cells
Long-noncoding RNAs (lncRNAs) play roles in regulating cellular functions. High-throughput sequencing analysis identified a new lncRNA, termed LAMTOR5-AS1, the expression of which was much higher in the chemos...
-
Article
Highly selective catalytic nitration of 1-nitronaphthalene with NO2 to 1,5-dinitronaphthalene over solid superacid SO42−/ZrO2 promoted by molecular oxygen and acetic anhydride under mild conditions
A simple and efficient method for liquid-phase catalytic nitration of 1-nitronaphthalene with NO2 to 1,5-dinitronaphthalene under mild conditions has been developed. The results indicated that the sulfated zircon...
-
Article
Open AccessFruit size control by a zinc finger protein regulating pericarp cell size in tomato
Fruit size is largely defined by the number and size of cells in the fruit. Endoreduplication – a specialized cell cycle – is highly associated with cell expansion during tomato fruit growth. However, how endo...
-
Article
Open AccessDecreased angiotensin receptor 1 expression in ± AT1 Knockout mice testis results in male infertility and GnRH reduction
This study aimed to detect the effect of angiotensin receptor 1 (AT1) knock out (KO) on spermatogenesis and hypothalamic-pituitary–gonadal (HPG) axis hormone expression.
-
Article
Mesoporous silicon sulfonic acid as a highly efficient and stable catalyst for the selective hydroamination of cyclohexene with cyclohexylamine to dicyclohexylamine in the vapor phase
In this work, a new mesoporous silicon sulfonic acid catalyst derived from silicic acid has been successfully prepared by the chemical bonding method. The physico-chemical properties of mesoporous silicon sulf...
-
Article
Open AccessDevelopment of the Sci-math Sensemaking Framework: categorizing sensemaking of mathematical equations in science
Scientific ideas are often expressed as mathematical equations. Understanding the ideas contained within these equations requires making sense of both the embedded mathematics knowledge and scientific knowledg...
-
Article
Development of a navigation performance evaluation system
-
Article
The spatial coding mechanism of ordinal symbols: a study based on the ordinal position effect
The ordinal position effect refers to a phenomenon in which items positioned early in an ordinal sequence receive a faster response with the left key than with the right key, and the opposite response pattern ...
