-
Article
Communities of practice for knowledge co-creation on sustainable dairy farming: features for value creation for farmers
Communities of Practice (CoPs) are a promising concept for transdisciplinary knowledge co-creation in sustainable agricultural development, but empirical evidence from the farmers’ viewpoint is scarce. This pa...
-
Article
Critères cliniques et thérapeutiques pris en compte lors de la prescription d’opioïdes forts: enquête dans le département du Finistère auprès de médecins généralistes et spécialistes
Définir les critères thérapeutiques et cliniques, ainsi que les obstacles et les contre-indications pris en compte lors de la prescription d’opioïdes forts (OF).
-
Article
Représentations mentales et comportements précédant la prescription d’opioïdes forts. Une enquête réalisée dans le département du Finistère auprès de 114 médecins généralistes et spécialistes
Près de 20 % des adultes souffrent de douleurs chroniques. Malgré l’existence de recommandations sur l’utilisation de la classe des opioïdes forts (OF), des barrières à la prescription existent. Pour comprendr...
-
Article
Risk factors for peripheral fractures vary by age in older men—the prospective MINOS study
Identification of older men at high risk of peripheral fracture can be improved by assessing prevalent fractures (men aged ≤65), history of falls (men aged >65), bone width, and aortic calcifications.
-
Article
Role of sex steroids in the regulation of bone morphology in men. The MINOS study
In ageing men, skeletal fragility is associated with reduced cortical thickness and decreased bone density. To better understand the role of testosterone and 17β-estradiol regarding these characteristics of sk...
-
Article
Insulin-Like Growth Factor I Is a Determinant of Hip Bone Mineral Density in Men Less Than 60 years of Age: MINOS Study
Several studies show that in elderly men bone mineral density (BMD) is not correlated with the insulin-like growth factor (IGF-I) level, but data are scanty in young men. Results of studies correlating insulin...
-
Article
Role of Vitamin D and Parathyroid Hormone in the Regulation of Bone Turnover and Bone Mass in Men: The MINOS Study
We investigated the role of vitamin D and of parathyroid hormone (PTH) in the regulation of bone mineral density (BMD), tone dimensions and seasonal variation of bone turnover in 881 men aged 19–85 years. Bone...
-
Article
Incidence of Limb Fracture across Europe: Results from the European Prospective Osteoporosis Study (EPOS)
The aim of this population-based prospective study was to determine the incidence of limb fracture by site and gender in different regions of Europe. Men and women aged 50–79 years were recruited from populat...
-
Article
Semiquantitative Evaluation of Prevalent Vertebral Deformities in Men and their Relationship with Osteoporosis: The MINOS Study
Epidemiologic studies have shown a high prevalence of vertebral deformities in men without a steep increase with aging, suggesting that a substantial number of these deformities are not related to osteoporosi...
-
Article
Prevalent Vertebral Deformity Predicts Incident Hip though not distal Forearm Fracture: Results from the European Prospective Osteoporosis Study
The presence of a vertebral deformity increases the risk of subsequent spinal deformities. The aim of this analysis was to determine whether the presence of vertebral deformity predicts incident hip and other...
-
Article
Specific signaling pathways in the regulation of TNF-α mRNA synthesis and TNF-α secretion in RBL-2H3 mast cells stimulated through the high affinity IgE receptor
Objective: In the present study, we investigated signal transduction pathways involved in TNF-α gene expression and TNF-α secretion by mast cells stimulated through the high affinity IgE...
-
Article
Mortality Associated with Vertebral Deformity in Men and Women: Results from the European Prospective Osteoporosis Study (EPOS)
Clinically apparent vertebral deformities are associated with reduced survival. The majority of subjects with radiographic vertebral deformity do not, however, come to medical attention. The aim of this study...
-
Article
Kinetics of protein phosphorylation and mediator secretion following antigen challenge of mast cells sensitized with monoclonal IgE or with reaginic serum
-
Article
Enhancement of the histamine releasing activity of mouse monoclonal anti-human IgE antibody xb6-16 when present in aggregated or complexed forms
FPLC purification of mouse monoclonal anti-human IgE antibody xb6-16 showed 2 major peaks of different molecular weight, peak 1 (>106 d) and peak 3 (1.6×105 d). Peak 1 consisted of IgG 1 and IgM, peak 3 of IgG 1 ...
-
Article
Monoclonal anti-human IgE: histamine release capacity and effect onin vitro sensitization of human basophils
IgE-anti-IgE complexes were formed by preincubation of a human myeloma IgE with a monoclonal anti-human IgE antibody at different concentrations. Binding of IgE onto the anti-IgE inhibited the histamine releas...
-
Article
Basophil sensitivity and reactivity to monoclonal anti-human IgE afterin vitro sensitization with human myeloma IgE
Leucocytes from human peripheral blood were acid eluted and sensitizedin vitro with increasing concentrations of radiolabelled myeloma IgE. This sensitization step was performed with or without 30% IgE depleted s...
-
Article
Passivein vitro sensitization of human basophils with dermatophagoides farinae specific IgE
Basophils from allergic or non-atopic donors were depleted for their native membrane IgE by acid treatment and then passively sensitized by Dermatophagoïdes farinae specific IgE containing sera. Histamine rele...
-
Article
Berichtigung
-
Article
Mein Stellung zur Grawitzschen Schlummerzellenlehre
-
Article
Beitrag zur Kenntniss der normalen und pathologischen Histologie der Decidua
