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Article
Open AccessArtificial Intelligence and Multiple Sclerosis
In this paper, we analyse the different advances in artificial intelligence (AI) approaches in multiple sclerosis (MS). AI applications in MS range across investigation of disease pathogenesis, diagnosis, trea...
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Article
Open AccessPredicting disease severity in multiple sclerosis using multimodal data and machine learning
Multiple sclerosis patients would benefit from machine learning algorithms that integrates clinical, imaging and multimodal biomarkers to define the risk of disease activity.
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Article
Recent advances in the longitudinal segmentation of multiple sclerosis lesions on magnetic resonance imaging: a review
Multiple sclerosis (MS) is a chronic autoimmune disease characterized by demyelinating lesions that are often visible on magnetic resonance imaging (MRI). Segmentation of these lesions can provide imaging biom...
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Article
Generic acquisition protocol for quantitative MRI of the spinal cord
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges, including a lack of standardized imaging protocols. Here we present a prospectively harmonized quantitative MRI protocol...
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Article
Open AccessAuthor Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
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Article
Open AccessAuthor Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
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Article
Open AccessRegional grey matter microstructural changes and volume loss according to disease duration in multiple sclerosis patients
The spatio-temporal characteristics of grey matter (GM) impairment in multiple sclerosis (MS) are poorly understood. We used a new surface-based diffusion MRI processing tool to investigate regional modificati...
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Article
Open AccessOpen-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This prot...
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Article
Open AccessLesion probability map** in MS patients using a regression network on MR fingerprinting
To develop a regression neural network for the reconstruction of lesion probability maps on Magnetic Resonance Fingerprinting using echo-planar imaging (MRF-EPI) in addition to
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Article
Open AccessRetinal and brain damage during multiple sclerosis course: inflammatory activity is a key factor in the first 5 years
Understanding of the role of focal inflammation, a treatable feature, on neuro-axonal injury, is paramount to optimize neuroprotective strategy in MS. To quantify the impact of focal inflammatory activity on t...
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Article
Open AccessModified connectivity of vulnerable brain nodes in multiple sclerosis, their impact on cognition and their discriminative value
Brain structural network modifications in multiple sclerosis (MS) seem to be clinically relevant. The discriminative ability of those changes to identify MS patients or their cognitive status remains unknown. ...
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Article
Open AccessTime efficient whole-brain coverage with MR Fingerprinting using slice-interleaved echo-planar-imaging
Magnetic resonance fingerprinting (MRF) is a promising method for fast simultaneous quantification of multiple tissue parameters. The objective of this study is to improve the coverage of MRF based on echo-pla...
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Chapter and Conference Paper
Contextual Diffusion Image Post-processing Aids Clinical Applications
Diffusion weighted magnetic resonance imaging ( dMRI) and tractography have shown great potential for the investigation of the white mater architecture in-vivo, especially with the recent advancements by usin...
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Article
Open AccessThe multiple sclerosis visual pathway cohort: understanding neurodegeneration in MS
Multiple Sclerosis (MS) is an immune-mediated disease of the Central Nervous System with two major underlying etiopathogenic processes: inflammation and neurodegeneration. The latter determines the prognosis o...