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Article
Open AccessPredicting disease severity in multiple sclerosis using multimodal data and machine learning
Multiple sclerosis patients would benefit from machine learning algorithms that integrates clinical, imaging and multimodal biomarkers to define the risk of disease activity.
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Article
Recent advances in the longitudinal segmentation of multiple sclerosis lesions on magnetic resonance imaging: a review
Multiple sclerosis (MS) is a chronic autoimmune disease characterized by demyelinating lesions that are often visible on magnetic resonance imaging (MRI). Segmentation of these lesions can provide imaging biom...
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Article
Open AccessAuthor Correction: BDNF Val66Met gene polymorphism modulates brain activity following rTMS-induced memory impairment
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Article
Open AccessBDNF Val66Met gene polymorphism modulates brain activity following rTMS-induced memory impairment
The BDNF Val66Met gene polymorphism is a relevant factor explaining inter-individual differences to TMS responses in studies of the motor system. However, whether this variant also contributes to TMS-induced m...
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Article
Generic acquisition protocol for quantitative MRI of the spinal cord
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges, including a lack of standardized imaging protocols. Here we present a prospectively harmonized quantitative MRI protocol...
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Article
Open AccessAuthor Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
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Article
Open AccessAuthor Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
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Article
Open AccessRegional grey matter microstructural changes and volume loss according to disease duration in multiple sclerosis patients
The spatio-temporal characteristics of grey matter (GM) impairment in multiple sclerosis (MS) are poorly understood. We used a new surface-based diffusion MRI processing tool to investigate regional modificati...
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Article
Open AccessOpen-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This prot...
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Article
Open AccessLesion probability map** in MS patients using a regression network on MR fingerprinting
To develop a regression neural network for the reconstruction of lesion probability maps on Magnetic Resonance Fingerprinting using echo-planar imaging (MRF-EPI) in addition to
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Article
Open AccessReduced hippocampal subfield volumes and memory performance in preterm children with and without germinal matrix-intraventricular hemorrhage
Preterm newborns with germinal matrix-intraventricular hemorrhage (GM-IVH) are at a higher risk of evidencing neurodevelopmental alterations. Present study aimed to explore the long-term effects that GM-IVH ha...
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Article
Open AccessRetinal and brain damage during multiple sclerosis course: inflammatory activity is a key factor in the first 5 years
Understanding of the role of focal inflammation, a treatable feature, on neuro-axonal injury, is paramount to optimize neuroprotective strategy in MS. To quantify the impact of focal inflammatory activity on t...
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Article
Open AccessModified connectivity of vulnerable brain nodes in multiple sclerosis, their impact on cognition and their discriminative value
Brain structural network modifications in multiple sclerosis (MS) seem to be clinically relevant. The discriminative ability of those changes to identify MS patients or their cognitive status remains unknown. ...
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Article
Open AccessLong-term exercise training improves memory in middle-aged men and modulates peripheral levels of BDNF and Cathepsin B
Aging is accompanied by a decline in memory and other brain functions. Physical exercise may mitigate this decline through the modulation of factors participating in the crosstalk between skeletal muscle and t...
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Article
Open AccessAdaptability and reproducibility of a memory disruption rTMS protocol in the PharmaCog IMI European project
Transcranial magnetic stimulation (TMS) can interfere with cognitive processes, such as transiently impairing memory. As part of a multi-center European project, we investigated the adaptability and reproducib...
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Chapter
Normal Hypocretin-1 (Orexin A) Levels in Cerebrospinal Fluid in Patients with Idiopathic Intracranial Hypertension
Aim: Low levels of hypocretin-1 (HC-1) have been associated with hypersomnia, obesity, depression, and chronic headaches. These conditions are frequently present in patients with idiopathic intracr...
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Chapter
Idiopathic Normal Pressure Hydrocephalus: Results of a Prospective Cohort of 236 Shunted Patients
Aim: To describe the outcomes and complication rates in 236 patients with idiopathic normal pressure hydrocephalus (INPH) after treatment.
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Article
Quality of life and neurobehavioral changes in survivors of malignant middle cerebral artery infarction
Malignant middle cerebral artery (MMCA) infarction is associated with a mortality rate of 80% under conservative treatment. Decompressive hemicraniectomy (DH) reduces mortality and improves the functional outc...
