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Article
Open AccessDeep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis
Routine childhood vaccination against measles, mumps and rubella has virtually abolished virus-related morbidity and mortality. Notwithstanding this, we describe here devastating neurological complications ass...
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Article
Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model
The impact of feto-maternal histocompatibility on reproduction has inspired long-lasting debates. However, after the review of numerous articles, the impact of HLA allele sharing within couples on fecundity re...
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Article
Open AccessHeterologous protection elicited by candidate monomeric recombinant HIV-1 gp120 vaccine in the absence of cross neutralising antibodies in a macaque model
Current data suggest that an efficacious human immunodeficiency virus type 1 (HIV-1) vaccine should elicit both adaptive humoral and cell mediated immune responses. Such a vaccine will also need to protect aga...
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Article
Characterisation of MHC haplotypes in a breeding colony of Indonesian cynomolgus macaques reveals a high level of diversity
Recent reports have revealed that cynomolgus macaques obtained from different geographic origins may be more or less suitable for particular studies depending on the specific question(s) being addressed, e.g. ...
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Article
Characterisation of Mhc class I and class II DRB polymorphism in red-bellied tamarins (Saguinus labiatus)
The infection of red-bellied tamarins (Saguinus labiatus) with GB virus B (GBV-B) is an important surrogate model of hepatitis C virus infection in man. To fully exploit the value of this model, we have character...
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Article
Mhc haplotype H6 is associated with sustained control of SIVmac251 infection in Mauritian cynomolgus macaques
The restricted diversity of the major histocompatibility complex (MHC) of Mauritian cynomolgus macaques provides powerful opportunities for insight into host-viral interactions and cellular immune responses th...
