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  1. Article

    Open Access

    Cardiovascular disease risk assessment and multidisciplinary care in prostate cancer treatment with ADT: recommendations from the APMA PCCV expert network

    Androgen deprivation therapy (ADT) is the mainstay approach for prostate cancer (PCa) management. However, the most commonly used ADT modality, gonadotropin-releasing hormone (GnRH) agonists, has been associat...

    Axel S. Merseburger, Ganesh Bakshi, Dong-Yi Chen, Edmund Chiong in World Journal of Urology (2024)

  2. No Access

    Article

    Cardiovascular risks of androgen receptor targeted agents in prostate cancer: a systematic review and meta-analysis

    Androgen receptor targeted agents (ARTA) have increasingly been incorporated into treatment regimens for various stages of prostate cancer. Patients are living longer with prostate cancer, and thus have a high...

    Chloe Shu Hui Ong, Yu ** Terence Law, Lin Kyaw in Prostate Cancer and Prostatic Diseases (2024)

  3. Article

    Open Access

    5-alpha reductase inhibitors and MRI prostates: actively reducing prostate sizes and ambiguity

    Magnetic resonance imaging (MRI) scans are increasingly first-line investigations for suspected prostate cancer, and essential in the decision for biopsy. 5-alpha reductase inhibitor (5-ARI) use has been shown...

    Ziting Wang, Kaiying Wang, Han Yang Ong, Woon Chau Tsang, Qing Hui Wu in BMC Urology (2023)

  4. No Access

    Article

    Utility of serum biomarkers for predicting cancer in patients with previous negative prostate biopsy

    To review the role of serum biomarkers: prostate-specific antigen (PSA), PSA density (PSAD), free:total PSA ratio, prostate health index (PHI) and PHI density (PHID), along with magnetic resonance imaging (MRI...

    Ziting Wang, Ming Tow Chan, Woon Chau Tsang, Edmund Chiong in World Journal of Urology (2022)

  5. Article

    Open Access

    Author Correction: PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

    Min Thura, Abdul Qader Al-Aidaroos, Abhishek Gupta, Cheng Ean Chee in Nature Communications (2021)

  6. Article

    Open Access

    Cost-effectiveness of MRI targeted biopsy strategies for diagnosing prostate cancer in Singapore

    To evaluate the cost-effectiveness of six diagnostic strategies involving magnetic resonance imaging (MRI) targeted biopsy for diagnosing prostate cancer in initial and repeat biopsy settings from the Singapor...

    Li-Jen Cheng, Swee Sung Soon, Teck Wei Tan, Cher Heng Tan in BMC Health Services Research (2021)

  7. No Access

    Article

    Transitioning to robotic partial nephrectomy with a team-based proctorship achieves the desired improved outcomes over open and laparoscopic partial nephrectomy

    Proctoring may facilitate a safe transition to robotic-assisted partial nephrectomy (RAPN) for centres performing open (OPN) and laparoscopic partial nephrectomies (LPN). This study compared the 5-year outcome...

    Asrif Chowdhury, Lincoln Guan Lim Tan, Edmund Chiong, Koon Ho Rha in Updates in Surgery (2021)

  8. Article

    Open Access

    PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

    Tumor-specific antibody drugs can serve as cancer therapy with minimal side effects. A humanized antibody, PRL3-zumab, specifically binds to an intracellular oncogenic phosphatase PRL3, which is frequently exp...

    Min Thura, Abdul Qader Al-Aidaroos, Abhishek Gupta, Cheng Ean Chee in Nature Communications (2019)

  9. No Access

    Reference Work Entry In depth

    Clinical Aspects and Investigations in Genitourinary Cancer

    Genitourinary cancer is an important topic in the current era. Understanding the disease is important to tailor the treatment for individual patients. Clinical aspects and investigations are part and parcel in...

    Pradeep Durai, Qing Hui Wu, Edmund Chiong in Urologic Oncology (2019)

  10. No Access

    Article

    Robotic kidney autotransplantation in a porcine model: a procedure-specific training platform for the simulation of robotic intracorporeal vascular anastomosis

    Robotic-assisted kidney transplantation (RKT) with the Da Vinci (Intuitive, USA) platform has been recently developed to improve outcomes by decreasing surgical site complications and morbidity, especially in ...

    Ho Yee Tiong, Benjamin Yen Seow Goh, Edmund Chiong in Journal of Robotic Surgery (2018)

  11. Article

    Open Access

    Restriction of in vivo infection by antifouling coating on urinary catheter with controllable and sustained silver release: a proof of concept study

    Catheter Associated Urinary Tract Infections are among the most common urological infections world-wide. Bacterial biofilms and encrustation cause significant complications in patients with urinary catheters. ...

    Kedar Diwakar Mandakhalikar, Rong Wang, Juwita N. Rahmat in BMC Infectious Diseases (2018)

  12. Article

    Open Access

    Extraction and quantification of biofilm bacteria: Method optimized for urinary catheters

    Bacterial biofilms are responsible for the failure of many medical devices such as urinary catheters and are associated with many infectious and non-infectious complications. Preclinical and clinical evaluatio...

    Kedar Diwakar Mandakhalikar, Juwita Norasmara Rahmat, Edmund Chiong in Scientific Reports (2018)

  13. No Access

    Living Reference Work Entry In depth

    Clinical Aspects and Investigations in Genitourinary Cancer

    Genitourinary cancer is an important topic in the current era. Understanding the disease is important to tailor the treatment for individual patients. Clinical aspects and investigations are part and parcel in...

    Pradeep Durai, Qing Hui Wu, Edmund Chiong in Urologic Oncology

  14. Article

    Open Access

    Erratum to: Quantitative 18F-fluorocholine positron emission tomography for prostate cancer: correlation between kinetic parameters and Gleason scoring

    Joshua D. Schaefferkoetter, Ziting Wang, Mary C. Stephenson in EJNMMI Research (2017)

  15. Article

    Open Access

    Quantitative 18F-fluorocholine positron emission tomography for prostate cancer: correlation between kinetic parameters and Gleason scoring

    The use of radiolabeled choline as a positron emission tomography (PET) agent for imaging primary tumors in the prostate has been evaluated extensively over the past two decades. There are, however, conflictin...

    Joshua D. Schaefferkoetter, Ziting Wang, Mary C. Stephenson in EJNMMI Research (2017)

  16. No Access

    Chapter

    Renal Cancer

    As the global incidence and mortality of kidney cancer increases, the treatment modalities of renal-cell carcinoma have also progressed over the last decade. There are improved surgical techniques, which aim t...

    Fiona Mei Wen Wu, Edmund Chiong in Tropical Hemato-Oncology (2015)

  17. No Access

    Article

    New therapies for non-muscle-invasive bladder cancer

    The treatment of non-muscle-invasive bladder cancer (NMIBC) remains a challenge owing to its increased tendency to recur and the possibility of progression to potentially dangerous muscle-invasive disease. Tre...

    Edmund Chiong, Kesavan Esuvaranathan in World Journal of Urology (2010)

  18. No Access

    Article

    Urinary markers in screening patients with hematuria

    Hematuria is a common presenting symptom of urothelial malignancy. Although conventional urine analysis is very sensitive in detecting the presence of hematuria, it is not specific in detecting bladder cancer ...

    Edmund Chiong, Kris E. Gaston, H. Barton Grossman in World Journal of Urology (2008)