13 Result(s)

Article

Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls

Although cerebellar involvement across a wide range of cognitive and neuropsychiatric phenotypes is increasingly being recognized, previous large-scale studies in schizophrenia (SZ) have primarily focused on s...

T Moberget, N T Doan, D Alnæs, T Kaufmann, A Córdova-Palomera… in Molecular Psychiatry (2018)

Article

Contribution of non-genetic factors to dopamine and serotonin receptor availability in the adult human brain

The dopamine (DA) and serotonin (5-HT) neurotransmission systems are of fundamental importance for normal brain function and serve as targets for treatment of major neuropsychiatric disorders. Despite central ...

J Borg, S Cervenka, R Kuja-Halkola, G J Matheson, E G Jönsson… in Molecular Psychiatry (2016)

Article

Common variant at 16p11.2 conferring risk of psychosis

Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as m...

S Steinberg, S de Jong, M Mattheisen, J Costas, D Demontis… in Molecular Psychiatry (2014)

Article

Expanding the range of ZNF804A variants conferring risk of psychosis

A trio of genome-wide association studies recently reported sequence variants at three loci to be significantly associated with schizophrenia. No sequence polymorphism had been unequivocally (P<5 × 10⁻⁸) associat...

S Steinberg, O Mors, A D Børglum, O Gustafsson, T Werge… in Molecular Psychiatry (2011)

Article

Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2

We and others have previously reported linkage to schizophrenia on chromosome 10q25–q26 but, to date, a susceptibility gene in the region has not been identified. We examined data from 3606 single-nucleotide p...

M C O'Donovan, N Norton, H Williams, T Peirce, V Moskvina… in Molecular Psychiatry (2009)

Article

Transcription factor AP-2β genotype, striatal dopamine D2 receptor density and cerebrospinal fluid monoamine metabolite concentrations in humans

Transcription factor AP-2β has been suggested to influence brain monoaminergic systems by regulating target genes. In order to explore a possible functional role, AP-2β genotype was analysed in relation to str...

M. Damberg, C. Berggård, L. Farde, G. C. Sedvall… in Journal of Neural Transmission (2004)

Article

No association between dopamine D4 receptor gene variants and Novelty Seeking

E G Jönsson, R Ivo, J P Gustavsson, T Geijer, K Forslund… in Molecular Psychiatry (2002)

Article

Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers

An association between long alleles of a variable number tandem repeat (VNTR) polymorphism in the dopamine receptor D4 gene and the extraversion related personality traits Excitement and Novelty Seeking has b...

M.-L. Persson, D. Wassermann, T. Geijer… in European Archives of Psychiatry and Clinic… (2000)

Article

Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers

The density of striatal dopamine D2 receptors has been shown to vary considerably among healthy subjects.¹ This variability might be due to genetic or environmental factors. In the present analysis we searched fo...

E G Jönsson, M M Nöthen, F Grünhage, L Farde, Y Nakashima… in Molecular Psychiatry (1999)

Article

Failure to replicate an association between a rare allele of a tyrosine hydroxylase gene microsatellite and schizophrenia

An association between schizophrenia and a rare perfect ten-repeat allele, K1_p, of a tetranucleotide microsatellite polymorphism in the tyrosine hydroxylase gene has recently been reported. The rare allele was fo...

E. G. Jönsson, Thomas Geijer… in European Archives of Psychiatry and Clinic… (1998)