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Article
Open AccessGlutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation
Concanavalin A (Con A)-induced hepatitis model is well-established experimental T cell-mediated liver disease. Reactive oxygen species (ROS) is associated with T-cell activation and proliferation, but continue...
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Article
Open AccessMucin 1-mediated chemo-resistance in lung cancer cells
Paclitaxel (PTX) is a commonly used drug to treat diverse cancer types. However, its treatment can generate resistance and the mechanisms of PTX-resistance in lung cancers are still unclear. We demonstrated th...
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Article
Open AccessLoss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development
Presenilins are the enzymatic components of γ-secretase complex that cleaves amyloid precursor protein, Notch and β-catenin, which has critical roles in the development of Alzheimer’s disease and cancer cell g...
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Article
Open AccessCystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity
Cystatin SN (CST1) is one of the several salivary cystatins that form tight equimolar complexes with cysteine proteases, such as the cathepsins. High expression of CST1 is correlated with advanced pTNM stage i...
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Article
Open AccessAntitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals
Cytokine and activation of lymphocytes are critical for tumor growth. We investigated whether interleukin (IL)-32β overexpression changes other cytokine levels and activates cytotoxic lymphocyte, and thus modify ...
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Article
Open AccessIL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals
Several studies have shown physiological functions of interleukin (IL)-32, a novel cytokine. However, the role of IL-32 in cancer development has not been reported. In this study, we showed that IL-32γ inhibit...
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Article
Protective effect of oxidative stress in HaCaT keratinocytes expressing E7 oncogene
In a previous study, we established a stable cell line which constitutively expresses E7 in HaCaT human keratinocyte cell line and identified various relevant factors including oxygen modulators affected by th...
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Article
Roughening transition of grain boundaries in metals and oxides
Extensive theoretical analysis and experimental observations show surface roughening transitions of crystals. The surface roughening is characterized by step free energy, which gradually decreases to 0 at the ...
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Article
Porous Organosilicates for On-Chip Dielectric Applications
Porous organosilicates useful for on-chip insulator applications can be prepared by templating the vitrification of low molecular weight silsesquioxanes (SSQs) using highly branched, thermally labile macromole...
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Chapter
Nanoporous Polyimides
Foamed polyimides have been developed in order to obtain thin film dielectric layers with very low dielectric constants for use in microelectronic devices. In these systems the pore sizes are in the nanometer ...
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Article
Templating Nanoporosity in Organosilicates Using Well-Defined Branched Macromolecules
A general route to organic-inorganic hybrids with nanophase morphologies has been elaborated with the objective of ultimately templating nanoporosity in organosilicates. A key feature of the hybrids is the pre...
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Article
Phase-Separated Inorganic-Organic Hybrids for Microelectronic Applications
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Article
Massive transformation in an Fe–Cu alloy
A typical microstructure characteristic of massive transformation such as “boundary crossing” and “irregular and jagged boundaries” was observed in an Fe–Cu alloy after water quenching and after cooling at a r...
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Article
Re-evaluation of optimal dose of contrast medium for vascular enhancement in CT of the head and neck
Adequate contrast enhancement of major neck vessels is more important than that of a tumour itself in CT of most head and neck tumours because of differentiation from neck node metastases. Our purpose was to ...
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Article
Polyimide Nanofoams For Low Dielectric Applications
Foamed polyimides have been developed in order to obtain thin film dielectric layers with very low dielectric constants for use in microelectronic devices. In these systems the pore sizes are in the nanometer ...
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Article
The effect of elastic misfit strain on the morphological evolution of γ’-precipitates in a model Ni-base superalloy
The morphological evolution of coherent γ’-precipitates in a Ni-23.4Co-4.7Cr-4Al-4.3Ti (wt%) alloy has been observed under systematically varying heat-treatment conditions. By deeply etching the matrix and obs...
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Article
Time-resolved SAXS studies of morphological changes in cold crystallized poly(ethylene terephthalate) during annealing and heating
Structural changes occurring during crystallization of quenched amorphous poly(ethylene terephthalate) (PET) and subsequent cooling/heating cycles have been studied by real-time small-angle x-ray scattering (S...
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Article
Effects of chemical structure and precursor on optical properties, thermo-mechanical properties, and molecular orientation and order of thin films of stiff aromatic polyimides
Thin films of rigid poly(p-phenylene pyromellitimide) (PMDA-PDA) and semi-rigid poly(p-phenylene biphenyltetracarboximide) (BPDA-PDA), prepared by thermal imidization of the respective poly(amic acid) and poly(am...
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Article
Driving force for deposition in the chemical vapour deposition process
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Article
The Morphological Changes of γ′ Precipitates in a Ni-8Al (wt pct) Alloy during their Coarsening
When a Ni-8A1 (wt pct) alloy is aged at 1020 °C (30 °C below the solvus temperature of about 1050 °C) by cooling directly from the solution-treatment temperature, theγ′ precipitates undergo Ostwald ripening from ...
