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Article
Effects of anti-resorptive drugs on implant survival and peri-implantitis in patients with existing osseointegrated dental implants: a retrospective cohort study
The effect of anti-resorptive drug (ARD) usage among patients with successful dental implant osseointegration is controversial. This study showed an increased risk of implant failure in ARD users. Risk factors...
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Article
Inhibition of breast cancer invasion by TIS21/BTG2/Pc3-Akt1-Sp1-Nox4 pathway targeting actin nucleators, mDia genes
The mammalian homolog of Drosophila diaphanous (mDia), actin nucleator, has been known to participate in the process of invasion and metastasis of cancer cells via regulating a number of actin-related biologic...
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Article
Open AccessConversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain
Survival and proliferation of cancer cells are often associated with hyperactivity of the serine/threonine kinase, Akt. Herein, we show that prosurvival activity of Akt can be converted into prodeath activity ...
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Article
Open AccessLoss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development
Presenilins are the enzymatic components of γ-secretase complex that cleaves amyloid precursor protein, Notch and β-catenin, which has critical roles in the development of Alzheimer’s disease and cancer cell g...
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Article
Open AccessProstate cancer bone metastases acquire resistance to androgen deprivation via WNT5A-mediated BMP-6 induction
Androgen ablation is the first-line therapy for patients with metastatic prostate cancer (CaP). However, castration resistance will eventually emerge. In the present study, we have investigated the role of bon...
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Article
Transient thermal analysis of a cryogenic oxidizer tank in the liquid rocket propulsion system during the prelaunch helium gas pressurization
The transient thermal behavior in the cryogenic oxidizer tank for the liquid propulsion system of the KSLV-I satellite launching space vehicle is theoretically investigated for the pressurization process by ga...
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Article
Open AccessNovel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1–PUMA pathway
DPC4 (deleted in pancreatic cancer 4)/Smad4 is an essential factor in transforming growth factor (TGF)-β signaling and is also known as a frequently mutated tumor suppressor gene in human pancreatic and colon can...
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Article
Improvement of horizontal macular contraction after surgical removal of epiretinal membranes
To determine whether horizontal macular contraction caused by epiretinal membranes (ERMs) improves after surgical removal.
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Article
Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells
p53 is frequently mutated by genetic alternation or suppressed by various kinds of cellular signaling pathways in human cancers. Recently, we have revealed that p53 is suppressed and eliminated from cells by d...
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Article
Role of CK1 in GSK3β-mediated phosphorylation and degradation of Snail
The epithelial to mesenchymal transition (EMT) that occurs during embryonic development has begun to attract attention as a potential mechanism for tumor cell metastasis. Snail is a well-known Zn-finger transc...
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Article
p53, secreted by K-Ras–Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker
p53 is eliminated from K-Ras-mutated cancer cells through direct interaction with Snail. However, it is not achieved through proteasome-mediated degradation or transcriptional repression. Here we provide evide...
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Article
Attachment Strength of Listeria monocytogenes and its Internalin-Negative Mutants
A single cell of Listeria monocytogenes attached on food contact surfaces can be a potential source of cross-contamination in a food-processing plant. To see whether internalin A (InlA) and B (InlB), major surfac...
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Article
Negative thermal quenching in undoped ZnO and Ga-doped ZnO film grown on c-Al2O3 (0001) by plasma-assisted molecular beam epitaxy
Negative thermal quenching (NTQ) was observed in bound exciton emission line in undoped ZnO and the donor-to-valence-band emission in heavily Ga-doped ZnO thin films grown on c-Al2O3 (1000) through low temperatur...
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Article
Cyclooxygenase-2 expression in human thyroid disease
Objectives: Cyclooxygenase (COX)-2, which is the inducible form of the COX enzyme for prostaglandin synthesis and a key mediator of epithelial cell growth, has been shown to be up-regulat...
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Article
Effect of Drinking-Water Administration of Experimental Chlorate Ion Preparations on Salmonella enterica serovar Typhimurium Colonization in Weaned and Finished Pigs
Foodborne disease caused bySalmonella is of public health and economic significance. In order to assess the practical effectiveness of a new intervention strategy, experimental chlorate preparations (ECP) were ad...
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Article
Alterations in hepatic metabolism of sulfur-containing amino acids induced by ethanol in rats
Alterations in hepatic metabolism of S-amino acids were monitored over one week in male rats treated with a single dose of ethanol (3 g/kg, ip). Methionine and S-adenosylhomocysteine concentrations were incre...
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Article
Skew-commuting and commuting map**s in rings
We study some maps which are skew-commuting or skew-centralizing on additive subgroups of rings with a left identity; and we present some results concerning commuting map**s in semiprime rings.¶ The first m...
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Diagnostics for the Kstar: Korea Super-Conducting Tokamak Advanced Research
The KSTAR (Korea Super-conducting Tokamak Advanced Research) [1,2] is aiming at the successful performance of the advanced tokamak (AT) mode and steady state operations. Though the AT mode can be realized in pres...
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Chapter
FDL Specifically Controls SoxS-Like Activation of NADPH: Ferredoxin Reductase in A. vinelandii
Previous studies have established that disruption of the fdxA gene that encodes A. vinelandii ferredoxin I (AvFdI) leads to overexpression of a small acidic protein. That protein has been purified, its gene has b...
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